The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $619,347 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Light Research Inc., a small for-profit company based in Tucson, Arizona. The grant supports the development and optimization of a compact, multimodal intraoral camera system that integrates polarized white light imaging, autofluorescence imaging, optical coherence tomography, and near-infrared transillumination imaging...
This $309,428 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), authorized under the Oral Diseases and Disorders Research program (CFDA 93.121), is supporting the development of an optical pH (oPH) imaging device for rapid, early-stage dental caries detection. The awardee, Veravanti Inc., aims to produce an oPH device that combines high-resolution color imaging with precise pH mapping of the oral cavity, allowing dentists to identify areas of...
This U.S. National Institute of Dental and Craniofacial Research (NIDCR) Project Grant award under the Oral Diseases and Disorders Research program (CFDA 93.121) provides $466,500.00 to the University of Colorado-Denver to develop body heat-activated, storable, near-infrared, self-illuminating nanoprobes for chemiluminescence imaging of cancer. The goal is to improve detection of micrometastatic disease and guide image-guided cancer surgery. The 3-year project will leverage these novel...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,297,941 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) federal grant program to the ADA Forsyth Institute, Inc. (The Forsyth Institute) to develop a novel dental restoration platform.
The key objectives are to create a self-improving dental adhesive, design bioactive dental composites with self-healing and antimicrobial properties, and produce CAD/CAM restoratives optimized for digital...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $421,800 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Midwestern University. The purpose of this 3-year grant, with a start date of September 7, 2023, is to develop hybrid hydrogel-based dental adhesives that are less vulnerable to hydrolytic degradation compared to current methacrylate-based alternatives. The goal is to create a truly biomimetic dental adhesive that can not...
This Project Grant, awarded by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program, will support a $3,471,873 collaborative research effort to develop a new class of anti-caries therapy. Specifically, the project aims to leverage species-specific susceptibilities to fluoride to create treatments that revert cariogenic dental biofilm dysbiosis, even under current levels of fluoride exposure from toothpastes and...
This $349,996 federal Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program aims to develop a new dental technology to improve oral health through microbial transplantation. The project will test the use of beneficial oral microbes from healthy donor dental plaque to treat conditions like dental decay and gum disease in recipients. The effort will employ a 3D printed system to grow and propagate the transplanted microbes, with...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, provides $164,255 to East Carolina University to develop and evaluate a new dental material intended to inhibit microbial biofilm formation and prevent secondary caries.
The key objectives are to: (1) synthesize a 2-aminoimidazole derivative, H10, and generate a new methacrylate-based antimicrobial agent containing the H10-HEMA...
The University of Kansas Center for Research Inc. was awarded a $467,008 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), to develop a novel non-invasive treatment for dental caries in children and patients with special needs. The project aims to create a biomimetic peptide-polymer interface that works synergistically with silver diamine fluoride (SDF) to arrest caries progression and...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $2,695,557 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) federal grant program to VIC Foundry Inc. to support the commercialization of VITAL-DENT, a regenerative pulp therapy for dental applications. The funded project aims to scale up the manufacturing process, optimize the formulation, and conduct in vivo studies and biocompatibility testing to support FDA clearance of the VITAL-DENT...