This $329,737 Project Grant awarded on September 12, 2023 by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), is supporting the development of a rapid, easy-to-use diagnostic platform for the point-of-care detection of high-risk HPV in saliva. The grantee, Innotech Precision Medicine, Inc., is working to create an innovative electrochemical biosensor that combines CRISPR-Cas12 technology with their proprietary gold-leaf electrodes to enable accurate, low-cost screening and monitoring of HPV infection, which is linked to most oropharyngeal squamous cell carcinoma cases. The project aims to develop a prototype multiplex assay capable of detecting HPV-16, HPV-18, and an optimal reference gene from saliva samples, addressing the need for improved early detection and management of HPV-related diseases.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $329.7k | 9/12/23 |