Harnessing coded ptychography to deliver AI-powered evaluation of unstained lung biopsies at the point-of-care

Ended Project Grant Awarded Last action

Award ID
R43CA278604
Recipient
Awarding agency
Obligated
$1,789,466

Award facts

Assistance listing
93.394 Cancer Detection and Diagnosis Research
Completion date
Funding
  • $1,389,883.00 Federal
  • $399,583.00 Non-federal
Place of performance
Seattle, WA 98121, USA

Award details come from USAspending.gov.

Description

Abstract
This small business innovation research (SBIR) phase I project aims to develop an imaging platform to analyze lung biopsy samples at the point of care. The system will immediately digitize unstained specimens and utilize computer-assisted detection/diagnostics to enable quick and efficient evaluations of samples by pathologists. The broad, long-term objective of this proposed research is to enable real-time diagnostics of pathology samples at the point-of-care. Early diagnosis and treatment of lung cancer is essential; the survival rate is low and is highly dependent on the stage of the disease. Primary diagnoses through microscopic analysis of biopsies (FNAS) have a 20-40% failure rate due to inadequate specimens. As a result, repeat biopsies must be performed causing delays in diagnosis and treatment up to 90 days, which is enough time for cancer to upstage and can reduce survivability by as much as 20%. Rapid- onsite (ROSE) assessment of the adequacy by a pathologist can guarantee the diagnostic quality of biopsies but is performed in

Transactions

Action Federal Non-federal Date
Amendment $0 $0
Amendment $95,567 $0
Amendment $95,567 $0
Amendment $399,583 $0
Amendment $399,583 $399,583
Original award $399,583 $0

Quick answers

Who received award R43CA278604?

R43CA278604 was awarded to Pathware Inc. by National Cancer Institute (National Institutes of Health) on September 7, 2022.

How much is award R43CA278604 worth?

$1,789,466 has been obligated on R43CA278604: $1,389,883 in federal funding and $399,583 in non-federal funding.

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