Project Grant R43AT010884

This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $857,216 to The Children's Hospital Corporation (Boston Children's Hospital) to conduct a longitudinal study on the neurodevelopmental trajectories leading to early symptoms of Attention Deficit Hyperactivity Disorder (ADHD) and disruptive behaviors in a socioeconomically disadvantaged, racially and ethnically diverse cohort of infants. The...

This Project Grant award of $1,541,456 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports a study on the neural mechanisms underlying the effects of menstrual cycle hormones on attention-deficit/hyperactivity disorder (ADHD) symptoms and cognition in young adult females with ADHD. The primary goals are to elucidate how menstrual cycle phase and hormonal changes impact the neural circuitry involved in response inhibition...

This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $673,803 to the University of Pittsburgh to study the relationship between parent-child neurobehavioral synchrony and the early development of Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms in preschool-aged children. The 5-year research project aims to identify neural and behavioral predictors of ADHD symptom trajectories, with a...

This $174,788 National Science Foundation (NSF) award under the Computer and Information Science and Engineering (CISE) program focuses on enhancing the assessment and diagnosis of Attention Deficit Hyperactivity Disorder (ADHD). The project aims to develop computational approaches to collect and analyze ADHD-related data, leveraging technologies such as inertial movement units, touch-sensitive screens, and high-precision cameras to gather insights into hyperactivity behaviors. The goal is to...

The National Institute of Mental Health (NIMH) awarded a Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The Children's Hospital Corporation, doing business as Boston Children's Hospital, for $2,535,618.00 with a project period from Aug 1, 2024 to Apr 30, 2029. The grant funding supports research aimed at improving the understanding of the genetic underpinnings of primary attention-deficit/hyperactivity disorder (ADHD) in families. Key objectives include: 1)...

This Project Grant award in the amount of $181,234 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will fund research to study the impact of early psychostimulant exposure on sleep neurophysiology and circadian rhythms in animal models of Attention-Deficit/Hyperactivity Disorder (ADHD). The research aims to break down the complex relationship between ADHD, psychostimulant medications like methylphenidate, and their...

This Project Grant award of $729,367 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research to assess the impacts of prescription stimulant drug shortages on health outcomes and disparities among youth with Attention-Deficit Hyperactivity Disorder (ADHD). The project aims to: 1) Measure the "amphetamine gap" and "stimulant gap" across communities and analyze their relationships with demographic,...

This federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA Program 93.242 (Mental Health Research Grants) provides funding to Nurelm Inc. to develop and test the LEMURDX system. LEMURDX is a software platform that uses machine learning and wearable device sensors to objectively measure hyperactivity in children with ADHD. The $615,908 award over 3 years will be used to refine the LEMURDX product to enhance ease of use for clinical researchers, and to test the...

This $1,309,500 Project Grant awarded by the National Institutes of Health (NIH) under the Trans-NIH Research Support (CFDA 93.310) program supports the development of a novel digital psychiatry diagnostic framework that utilizes crowdsourcing algorithms to improve the specificity of machine learning models in distinguishing between autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in adolescents. The key products and services to be delivered under this 3-year...

This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $400,000 to Mountainpass Technology LLC to develop and evaluate a customized version of the "MyTrials" remote biomarker capture system for use in decentralized clinical trials (DCTs) for substance use disorders (SUDs). The key products and services to be delivered include: 1) Refinement of the existing MyTrials prototype to support the...