Project Grant R43AR078728
- This Project Grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) to Scripps Health will develop and test prototype "smart" shoulder implants capable of continuously monitoring prosthesis loading conditions in real-time. The $317,259 award aims to create self-powered sensor systems for both humeral stem and glenosphere components, which can provide biofeedback to patients and data to healthcare providers to help reduce the need for revision surgeries in total...
- This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $293,811 to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University to conduct a 5-year study on the effect of rotator cuff repair (RCR) healing on the progression of degenerative shoulder changes and longer-term clinical outcomes. The key objectives of...
- This NIH Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) provides $308,927 to Tensense LLC to develop and evaluate an intraoperative device that directly measures ligament engagement during total knee arthroplasty. The key products to be delivered are: Integration of a handheld ligament tensiometer into a custom joint distractor to create an "integrated distraction tensiometer" device. This device will be calibrated and evaluated...
- This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $613,744 to Assistive Technology Development Inc. to develop a lightweight, cost-effective robotic telerehabilitation device for patients with musculoskeletal conditions. The device will provide motorized exercise modes coupled with blood flow restriction to enhance the...
- This $525,920 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) aims to develop a new generation of smart hip implants equipped with tiny sensors that monitor the forces acting on the implant during daily activities. The sensors, which generate their own power from movement, will wirelessly send data to doctors, allowing for early detection of potential problems like loosening or wear before they become serious. The project will optimize...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Rehabnetics Medical LLC will fund the development of a prototype robotic wrist-hand exoskeleton device for physical therapy. The system aims to provide tailored rehabilitative exercises and quantified measures of therapeutic progress for patients with motor deficits resulting from neurological conditions such as stroke, traumatic brain injury, and Parkinson's...
- This National Science Foundation Technology, Innovation, and Partnerships grant award of $250,000 provides funding from August 15, 2022 to July 31, 2024 to develop and evaluate an absorbable surgical adhesive patch to reinforce internal suture lines in the urinary tract. The University of California, Los Angeles will receive the award to create a flexible, bioabsorbable internal suture reinforcement device aimed at significantly reducing post-operative complications and readmissions for...
- The National Science Foundation awarded a $750,000 Project Grant to Rutgers, The State University under the Engineering program (CFDA 47.041) from September 1, 2022 to August 31, 2025. The grant funds research to develop an injectable nanoparticle therapy to restore strength and length to damaged tendons and ligaments. Specifically, the university will investigate combining a thermosensitive polymer and crosslinking agent to stabilize joints by quickly strengthening and returning tissues like...
- This $556,160 Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (CFDA 93.846) aims to examine the efficacy of a rehabilitation approach called Rehabilitation with Exercise and Psychological Support (REPS) for patients who have undergone ACL reconstruction surgery. The REPS intervention integrates standard exercise rehabilitation with psychological support, including clinician training, patient education videos, and techniques like...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) has awarded Collamedix Inc. a $300,000 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to establish the feasibility of their "CollaLink" collagen-based scaffold for augmenting primary repair of anterior cruciate ligament (ACL) mid-substance tears. The project aims to demonstrate that the CollaLink scaffold, when placed around an ACL tear, can provide a...
REAL-TIME FEEDBACK FOR POST-OPERATIVE REHABILITATION OF ROTATOR CUFF REPAIRS USING WIRELESS FORCE-SENSING SUTURE ANCHORS - ABSTRACT THE EMERGING INTERDISCIPLINARY RESEARCH FIELD OF REGENERATIVE REHABILITATION IS BASED ON RECENT EVIDENCE THAT POST-OPERATIVE REHABILITATION IS AS IMPORTANT AS SURGICAL TECHNIQUE TO ACHIEVE OPTIMAL FUNCTIONAL RESTORATION FOLLOWING ORTHOPEDIC INJURIES. DESPITE THIS RECOGNITION, CURRENT REHABILITATION PROTOCOLS REMAIN PRIMARILY BASED ON QUALITATIVE PRIOR EXPERIENCE OR PREFERENCES AND LACK PATIENT-SPECIFIC, REAL-TIME QUANTITATIVE FEEDBACK. THE GOAL OF THIS PROJECT IS TO DEVELOP A SENSING SYSTEM THAT CAN MONITOR THE LOCAL MECHANICAL ENVIRONMENT AT ORTHOPEDIC REPAIR SITES, SPECIFICALLY ROTATOR CUFF SURGERIES, THUS PROVIDING QUANTITATIVE FEEDBACK FOR SURGEONS AND PHYSICAL THERAPISTS (PTS) TO IMPROVE PATIENT OUTCOMES AND REDUCE COST BY OPTIMIZING REHABILITATION TIME AND REDUCING RATES OF FAILURE AND REVISION SURGERIES. THE SENSOR WOULD HAVE OTHER APPLICATIONS IN LARGE TENDON RECONSTRUCTION AND REHABILITATION SUCH AS ACHILLES TENDON REPAIR AS WELL. THE SENSING SYSTEM IS BASED ON BATTERY-FREE SENSORS EMBEDDED IN SUTURE ANCHORS USED FOR ROTATOR CUFF REPAIRS. THE SUTURE ANCHOR IS WIRELESSLY MONITORED WITH A WEARABLE DEVICE, ALLOWING REAL-TIME, CONTINUOUS BIOFEEDBACK FOR SURGEONS AND PTS TO MAKE INFORMED DECISIONS AND ACCURATELY APPLY EVIDENCE-BASED CARE. TO OUR KNOWLEDGE, THERE IS NO COMPARABLE TECHNOLOGY THAT CAN PERFORM SIMILAR TASKS EFFICIENTLY, AND SUCCESSFUL IMPLEMENTATION OF OUR SYSTEM COULD LEAD TO SIGNIFICANT COST SAVINGS IN THE ORTHOPEDIC INDUSTRY. WE HAVE PERFORMED PRELIMINARY EXPERIMENTS SHOWING THE TECHNICAL FEASIBILITY, AND CONDUCTED OVER 100 CUSTOMER INTERVIEWS CONFIRMING THE NEED AND MARKET OPPORTUNITY OF THIS TECHNOLOGY. WE HAVE ALSO SET UP A FUNDING STRATEGY AND COLLABORATORS FOR CONTINUING STUDY THE EFFECTIVENESS AND COMMERCIALIZATION OF THIS TECHNOLOGY. THE GOAL OF THIS PHASE I PROJECT IS TO DEVELOP AND EVALUATE THE SENSOR SYSTEM, AS WELL AS CONDUCT AN EX VIVO EXPERIMENT TO DEMONSTRATE THE FUNCTIONALITY AND PRACTICALITY OF THE DEVICE- INTEGRATED SENSOR.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | ($146) | 2/9/24 | ||
| Not listed | $0 | 11/3/22 | ||
| Not listed | $0 | 11/3/22 | ||
| Not listed | $0 | 11/3/22 | ||
| Not listed | $250.7k | 6/7/21 |