Project Grant R43AI174492
- This $1,016,000.00 Project Grant award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program will fund the development and application of a low-cost, portable biosensing platform for detecting and monitoring waterborne pathogens in aquaculture and coastal environments. The University of Massachusetts Lowell, as the prime awardee, will lead the effort to adapt its patented biosensing technology to enable real-time pathogen detection and...
- Micropure Genomics Inc. received a $274,199 Project Grant award from the National Science Foundation to advance methods for rapid, end-to-end sample preparation for sequencing applications. Under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the company will develop an automated process relying on electro-hydrodynamic trapping to isolate genomic material like DNA or RNA from cells in a flow cartridge. The process aims to significantly reduce preparation time while...
- This SBIR Phase I Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program provides $304,950 to Dayzero Water LLC to develop an effective, affordable, ultraviolet (UV) water treatment device. The project aims to create a simple, countertop appliance that uses UV light disinfection technology to produce safe drinking water, even when a community's water infrastructure is damaged by natural disasters. Key objectives include...
- Under this U.S. Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA) Small Business Innovation Research (SBIR) Phase 2 project, Ondavia, Inc. is developing, prototyping, validating, and commercializing an in-line, automated, semi-continuous instrument to monitor and measure the nitrogen cycle in water using Surface-Enhanced Raman Spectroscopy (SERS). The $600,000 award supports the assembly and testing of a prototype analyzer for automated, quantitative analysis...
- This $165,507 federal Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Small Business Innovation Research (SBIR) Program (CFDA 10.212) supports the development and validation of an affordable, handheld quantitative fluorometer and colorimeter system. This technology will enable rapid, field-based enumeration of E. coli and antibiotic-resistant E. coli in agricultural water samples, providing a more accessible alternative to...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award supports the development of a novel device that can rapidly and automatically extract pathogen DNA from whole blood samples to enable faster diagnosis of sepsis. The $274,858 award to New England Hemolytics, Inc., with a project period from September 1, 2024 to February 28, 2025, will fund the testing and optimization of this technology across common sepsis-causing pathogens. The...
- This Project Grant award from the U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) under the Small Business Innovation Research (SBIR) / Small Business Technology Transfer (STTR) Program (CFDA 10.212) provides $649,763 to Varigen Biosciences Corp to develop the AQPATHDX kit. This novel multiplex molecular diagnostic assay enables rapid, on-site detection of the most common catfish and tilapia pathogens in less than 30 minutes. The AQPATHDX kit utilizes...
- This $256,000 Project Grant from the National Science Foundation's Division of Industrial Innovation, under the Engineering program (CFDA 47.041), funds the development of a rapid, simple, and low-cost Salmonella detection and quantification test. Secure Food Solutions, Incorporated will optimize a multi-layer 96-well microplate method to demonstrate 90% sensitivity and specificity for Salmonella in raw poultry and processing environment samples within 15 hours without pre-enrichment. They...
- Federal Grant Award Summary Microsensor Labs, LLC received a $181,500 Phase I Project Grant from the Institute of Food Safety and Nutrition under the Small Business Innovation Research (SBIR) Program (CFDA 10.212) to develop Magicyte MB, a fully automated system for the rapid detection, enumeration, and isolation of Salmonella in food products. The award, effective September 30, 2025, with a completion date of May 30, 2026, supports validation testing of this innovative technology using novel...
- Coastaloceanvision Inc. was awarded a $300,000 Small Business Innovation Research (SBIR) Project Grant from the National Oceanic and Atmospheric Administration to develop a novel surface enhanced Raman spectroscopy (SERS) technology for rapidly detecting and quantifying human pathogens in seafood. The SERS technology uses a higher energy laser wavelength, an innovative mixture of silver-coated nanoparticles, and a fiber optic probe designed for direct use on seafood tissues and environmental...
PORTABLE SCALED SAMPLE PREPARATION DEVICE FOR CONCENTRATION AND RECOVERY OF BACTERIAL CONTAMINANTS - PROJECT SUMMARY THE OVERALL GOAL OF THIS SBIR PROJECT IS TO ESTABLISH THE TECHNICAL FEASIBILITY FOR COMMERCIALIZATION OF A PATENT-PENDING SAMPLE PREPARATION TECHNOLOGY THAT CONCENTRATES AND RECOVERS MICROBIAL CONTAMINANTS FROM APPROPRIATELY SCALED WATER SAMPLES. THE PROPOSED PRODUCT IS AFFORDABLE, VERSATILE, REUSABLE, PORTABLE, AND AUTOMATED DEVICE WITH NO MOVING PARTS, SUITABLE FOR ON-SITE OR IN-FIELD SAMPLE PREPARATION. RECOVERED ELUENTS RESULTED FROM THE SAMPLE PREPARATION CAN BE DELIVERED INTO MICROSCALE TESTS. PHASE I SPECIFIC AIMS ARE TO EVALUATE THE FEASIBILITY OF DEVELOPING A PORTABLE AUTOMATED SAMPLE PREPARATION DEVICE THAT CAN BE SCALED UP TO PROCESS LARGER VOLUME SAMPLES, DEVELOP READY-TO-USE BUFFER CONCENTRATES FOR IMPROVING CONCENTRATION AND RECOVERY OF BACTERIA, AND OBTAIN A PROOF OF CONCEPT FOR DETECTING LOW LEVELS OF BACTERIAL CONTAMINANTS, BY COMBINATION OF THE PROPOSED SAMPLE PREPARATION DEVICE AND RAPID MOLECULAR TEST. IN ADDITION TO OUTBREAKS LINKED TO RECREATIONAL AND DRINKING WATER, PRODUCE AND FOOD CONTAMINATIONS BY PATHOGENS FROM IRRIGATION AND OTHER AGRICULTURAL WATER ARE AN INCREASING CONCERN. EARLY DETECTION AND ROUTINE SURVEILLANCE IS OF PARAMOUNT IMPORTANCE FOR EFFECTIVE MANAGEMENT OF WATER OR FOODBORNE INFECTIOUS DISEASES. HOWEVER, CURRENT STANDARD PRACTICES ARE TIME CONSUMING, LARGELY DUE TO THE REQUIREMENT OF EXTENSIVE SAMPLE PREPARATION. THE PROPOSED TECHNOLOGY WOULD BE ABLE TO OVERCOME MAJOR LIMITATIONS OF CONVENTIONAL SAMPLE PREPARATION METHODS, ENABLE DETECTION OF LOW LEVELS OF BACTERIA IN DIFFERENT WATER OR LIQUID SAMPLE TYPES, AND EXPAND THE WIDESPREAD AND MEANINGFUL USE OF RAPID, PORTABLE DETECTION PLATFORMS.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | ($32k) | 8/4/25 | ||
| Not listed | $259.6k | 4/25/23 |