Project Grant R43AI167394

Award Date 7/8/22
Completion Date 6/30/23
Dollars Obligated $597K
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
CRYSTAL CITY, CA 90220, USA
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The National Institute of Allergy and Infectious Diseases (NIAID) awarded Inhalon Biopharma, Inc. a $1,024,926 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to complete non-clinical activities associated with a Phase 1 clinical study for their inhaled monoclonal antibody therapy, IN-002, targeted at treating respiratory syncytial virus (RSV) infections. The funded activities include processing clinical trial biospecimens to determine drug levels,...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,024,942 Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) to Inhalon Biopharma, Inc. to support the development of an inhaled monoclonal antibody therapy called IN-003 for treating human metapneumovirus (MPV) infection. The grant funding will enable Inhalon to produce a GLP-compliant batch of the IN-003 antibody treatment and conduct key IND-enabling studies required by the FDA before advancing...
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NICLOSAMIDE FORMULATIONS FOR THE TREATMENT OF INFLUENZA INFECTIONS - PROJECT SUMMARY THE PRINCIPAL GOAL OF THIS PROJECT IS TO DEMONSTRATE THAT THE FDA-APPROVED ANTHELMINTHIC DRUG, NICLOSAMIDE, CAN BE REFORMULATED IN A SYNTHETIC LUNG SURFACTANT WHICH CAN BE AEROSOLIZED FOR THE TREATMENT OF INFECTIONS CAUSED BY RESPIRATORY VIRUSES. THE STUDIES PROPOSED IN THIS SBIR PHASE I APPLICATION WILL BE FOCUSED ON TESTING THIS CONCEPT BY SUSPENDING NICLOSAMIDE LOADED LIPOSOMES IN OUR PROPRIETARY LUNG SURFACTANT TECHNOLOGY (NICLOSURF) AND TESTING CANDIDATE NICLOSURF FORMULATIONS IN A MOUSE INFLUENZA CHALLENGE MODEL. THE EFFECTIVENESS OF NICLOSURF AS A TREATMENT FOR RESPIRATORY VIRAL INFECTIONS CAUSED BY INFLUENZA WILL BE EVALUATED.

Posted 7/8/22, 12:00 AM