Project Grant R43AI129113

L2 Diagnostics LLC received a $293,142 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 21, 2025, with a completion date of August 31, 2027. The award supports development of a rapid diagnostic test (RDT) in lateral flow assay (LFA) format for detecting Babesia microti infection. The test targets BMGPI12 (BMSA1), a secreted protein released into the...

The National Science Foundation (NSF) awarded a $550,000 Project Grant under the NSF Technology, Innovation, and Partnerships (TIP) program to the University of California, Los Angeles (UCLA) to develop a rapid, multiplexed diagnostic tool for serological testing of tick-borne diseases (TBDs). This 2-year project seeks to improve blood-based detection of TBDs, including Lyme disease, Babesia, Anaplasma, and relapsing fever, through an innovative point-of-care (POC) serological assay. The goal is...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support the development of a novel universal rapid test for HIV diagnosis. IGE Immunodiagnostics & Therapeutics, LLC, a minority-owned small business, will receive $294,948 to adapt their existing HIV ELISA test into a 5th generation antigen/antibody combination rapid test format. The goal is to create a simple, rapid,...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award supports the development of a novel device that can rapidly and automatically extract pathogen DNA from whole blood samples to enable faster diagnosis of sepsis. The $274,858 award to New England Hemolytics, Inc., with a project period from September 1, 2024 to February 28, 2025, will fund the testing and optimization of this technology across common sepsis-causing pathogens. The...

This federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $308,000 in funding to Purdue University to develop new diagnostic technologies for detecting the Cyclospora cayetanensis parasite, which often contaminates produce and can lead to disease outbreaks. The key objectives are to: (1) discover DNA aptamers that can specifically recognize and bind to Cyclospora cayetanensis, and (2) integrate these aptamers into a paper-based...

This $270,128 SBIR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a low-cost, field-use DNA-based rapid diagnostic device for detecting plant diseases. The project aims to create a user-friendly, battery-operated testing kit that allows farmers to quickly identify diseases like citrus greening in their fields, enabling early intervention and more sustainable farming practices. The 9-month...

This National Science Foundation (NSF) Biological Sciences grant award provides $2,225,964 to the Georgia Tech Research Corporation (Georgia Tech) to develop a novel biosensing platform called "protocell communities" that can be used for rapid, low-cost medical diagnostics. The project aims to create a tool that can diagnose medical conditions by detecting and integrating multiple indicator molecules, addressing limitations of single-analyte diagnostics. The protocell technology uses...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $238,500 Project Grant under the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program to the University of California, San Diego (UCSD) to develop a novel electrochemical lateral flow assay (ELFA) for diagnosing tuberculosis (TB) from a single drop of blood. The objective is to create a highly sensitive and specific point-of-need TB detection test that can accurately distinguish active TB from...

This $389,782 Cooperative Agreement award from the United States Department of Agriculture's Animal and Plant Health Inspection Service (APHIS), under the Plant and Animal Disease, Pest Control, and Animal Care program (CFDA 10.025), aims to develop highly specific and validated TaqMan assays for the simultaneous detection of two critical shrimp diseases: Hepatopancreatic Microsporidiosis (HPM) caused by Enterocytozoon hepatopenaei (EHP) and Acute Hepatopancreatic Necrosis Disease (AHPND) caused...

Imcare Biotech, Inc. received a $364,763 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394) awarded June 20, 2025, with a completion date of May 31, 2026. The grant funds development and validation of SerAvue AI, a novel multi-analyte algorithmic assay diagnostic designed for early detection of hepatocellular carcinoma (HCC). The diagnostic combines Imcare Biotech's proprietary LC-SPIK biomarker with established markers...