Project Grant R43AI093018

This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to RT Microdx Inc. provides $274,362 to develop a novel molecular diagnostic platform for detecting respiratory diseases like strep throat. The platform aims to provide laboratory-quality accuracy for at-home use by non-healthcare professionals. Key technical objectives include optimizing the sensitivity of the platform's pH-sensitive polymer detection mechanism and ensuring robust performance at...

This $960,000 National Science Foundation project grant supports the development of a multiplexed plasmon-enhanced lateral flow assay for point-of-care detection of SARS-CoV-2 RNA and antigens. Funded under the NSF Engineering program (CFDA 47.041), the grantee, Washington University, will design, validate and build a novel diagnostic platform with sensitivity exceeding standard laboratory tests. Key deliverables include an ultrasensitive multiplexed lateral flow assay for simultaneous...

This National Science Foundation Technology, Innovation, and Partnerships Project Grant totaling $265,999 will support Rutgers, The State University of New Jersey, Camden in developing a rapid and reliable point-of-care screening for infectious diseases such as COVID-19. Specifically, the university will demonstrate a mass screening method to rapidly detect viruses to identify early infected individuals for quarantine. This work will enable rapid and reliable point-of-care detection with...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support the development of a novel universal rapid test for HIV diagnosis. IGE Immunodiagnostics & Therapeutics, LLC, a minority-owned small business, will receive $294,948 to adapt their existing HIV ELISA test into a 5th generation antigen/antibody combination rapid test format. The goal is to create a simple, rapid,...

Federal Cooperative Agreement Summary Prompt Diagnostics, Inc. received a $1.25M Cooperative Agreement from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), awarded June 15, 2025, with completion targeted for May 31, 2027. The company is developing an automated, multiplexed point-of-care diagnostic platform for rapid detection and quantification of Treponema pallidum infections (syphilis). The solution integrates magnetic...

This $788,406 project grant from the National Institutes of Health National Institute of Allergy and Infectious Diseases, under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund the development of a sensitive, direct reading bioaerosol detection platform to quantify airborne pathogens such as SARS-CoV-2. Aerosol Devices Inc. will integrate their gentle condensation-growth capture sampler, which concentrates intact, viable virus particles into a small liquid volume...

Controlpoint Inc. was awarded a $256,000 Project Grant from the National Science Foundation to develop a rapid, single-use, point-of-care lateral flow device for detecting kennel cough pathogens. The one-year award, made under the NSF Technology, Innovation, and Partnerships program, will support test validation, prototype manufacturing, and clinical evaluation to demonstrate the feasibility of detecting multiple bacteria and viruses associated with kennel cough in a single diagnostic test....

Federal Project Grant Award Summary Pearl Diagnostics, Inc. received a $999,316 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 24, 2025. The award supports development and commercialization of a rapid point-of-care lateral flow device (LFD) urine test for diagnosing invasive aspergillosis (IA), a critical public health threat recently designated by the World Health...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Quarksen LLC provides funding to develop an affordable, point-of-care diagnostic device for detecting viral and non-viral sexually transmitted infections (STIs) such as chlamydia, gonorrhea, syphilis, HIV, hepatitis C, and trichomoniasis. The project aims to create a device with an array of sensors that can rapidly and accurately detect STI biomarkers from cervical...

This National Science Foundation (NSF) Partnerships for Innovation - Research Partnerships (PFI-RP) project grant, CFDA #47.084, provides $549,649 to the University of Rochester to advance the development of a novel membrane-based sensor technology for the rapid and specific detection of infectious pathogens in biofluids. The project aims to integrate the membrane sensor into a hand-operated microfluidic device with a colorimetric readout, and demonstrate the generalizability of the approach...