The National Institute on Aging (NIA) awarded a $490,262 Project Grant (CFDA 93.866 - Aging Research) to Plans4Care Inc. on June 15, 2025 to develop and test a digital platform called "Activities4Care". The platform aims to provide customized, evidence-based activity plans for caregivers of people living with Alzheimer's disease and related dementias. The key products to be delivered under this Fast-Track SBIR award include: A clickable prototype of the Activities4Care platform that...
This $1,230,000 Project Grant awarded by the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866) will support the development and deployment of closed-loop digital interventions through a remote clinical trials platform. The overarching goal is to leverage technology to facilitate memory and cognitive function and prevent or delay age-related cognitive decline, particularly in older adults at risk of Alzheimer's disease and related dementias. The...
The National Institute on Aging (NIA) awarded a $864,674 Project Grant under the Aging Research program (CFDA 93.866) to Lifebio Inc., a small disadvantaged business, to develop a tablet-based platform called LifeBioTalk. This Phase I SBIR project aims to build a prototype of LifeBioTalk, which will provide stimulating audiovisual content narrated by a human-like avatar to engage people with Alzheimer's disease and related dementias (AD/ADRD). The prototype will have the ability to record...
This federal Project Grant award from the National Institute on Aging (NIA), under CFDA 93.866 Aging Research, is providing $509,038 to Ceiba Bio Inc. to develop a blood-based exercise mimetic as a potential treatment for Alzheimer's disease and related dementias. The key objectives are to: 1) identify 3 lead recombinant human GPLD1 molecules, 2) establish optimal exposure through in vivo PK profiling in aged mice, and 3) test 1 primary and 1 alternate lead GPLD1 molecule for disease...
The National Institute on Aging (NIA), under the Federal Aging Research program (CFDA 93.866), awarded a $245,148 project grant to Eyenexo LLC to develop an automated rodent behavior testing system for non-invasively assessing early-stage Alzheimer's disease (AD). The project aims to develop a behavior biomarker that can differentiate AD from normal aging by studying defensive behaviors triggered by looming stimuli, which are linked to early AD pathology in the midbrain region. The 2-year...
This Project Grant award of $835,056, provided by the National Institute on Aging (CFDA 93.866 Aging Research), supports the development of a multi-modal system of wearable biosensors and predictive analytics to enable continuous monitoring of mobility and cognitive function in older adults. The primary goals are to: Develop a system of flexible, breathable, and inconspicuous eutectogel sensor patches that can provide real-time monitoring of biophysical domains like gait, posture, heart rate,...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $811,228 to B.A. Maze, Inc. to develop the At-Home Health Station (AHS), a plug-and-play modular system designed to simplify digital health experiences for individuals with cognitive impairment or Alzheimer's disease and related dementias (CI/ADRD). The AHS system aims to promote health function and independence through remote patient monitoring, while also providing caregivers a platform for...
The National Institute on Aging (NIA) awarded a Project Grant (CFDA 93.866 - Aging Research) in the amount of $661,016 to the University of Southern California (USC) to develop a "Federated Deep Learning to Accelerate Alzheimer's Disease Research" project. The key products and services to be delivered include: Establishing an international "Federate AD" alliance to leverage innovative AI techniques and distributed computation to study Alzheimer's disease (AD) across large,...
The National Institute on Aging (NIA) awarded a $514,862 Project Grant (CFDA 93.866 - Aging Research) to Neuroindx, a for-profit, woman-owned small business, to develop an on-chip functional assay for identifying candidate microtubule-binding drugs to treat Alzheimer's Disease and related disorders (ADRDs). The goal of the project is to create an in vitro assay that can replicate key features of the neuronal microtubule microenvironment and use kinesin-based readouts to measure the ability of...
This $1,177,500 federal Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) supports the Arizona State University (ASU) Roybal Center for Older Adults Living Alone with Cognitive Decline. The center will develop and conduct clinical trials of technology-enabled behavioral and lifestyle interventions to delay Alzheimer's disease and related dementias (ADRD) and improve quality of life in older adults living alone with cognitive decline,...