The National Institute on Aging (NIA) awarded a $295,923 Project Grant (CFDA 93.866 - Aging Research) to Larix Bioscience LLC to develop novel hormonal therapeutics and study their efficacy with adult stem cells for the treatment of chronic pressure ulcers. The project aims to generate stable, bioactive hormone fusion biologics and evaluate their ability to enhance tissue regeneration in pressure ulcer patients, both alone and in combination with adipose-derived or induced pluripotent stem cells. Key deliverables include in vitro and in vivo testing of the engineered hormone therapeutics, as well as conducting preclinical toxicity studies. This research seeks to identify safe and effective anti-pressure ulcer treatment regimens that could advance to further preclinical and clinical development.
Generated 8/13/24, 7:19 AM