Exodots for diagnostic evaluation and monitoring of alzheimer's disease

Ended Project Grant Awarded Last action

Award ID
R43AG080878
Recipient
Awarding agency
Obligated
$291,692

Award facts

Assistance listing
93.866 Aging Research
Completion date
Originally
Place of performance
Berkeley, CA 94710, USA

Award details come from USAspending.gov.

Description

Abstract
Alzheimer's disease (ad) is the most widespread neurodegenerative disorder. Despite the severity of the disease, early diagnosis of ad is still challenging due to the low accuracy or high cost of neuropsychological tests and neuroimaging. Development of an accurate and cost-effective technology for non-invasive screening and monitoring of ad before irreversible brain damage or mental decline is critical. Wellsim proposes to develop and validate a highly sensitive immunofluorescence assay, termed exodots, for detection and quantification of ad core biomarkers from circulating extracellular vesicles (EV) with high accuracy, high speed, and low cost. This blood-based assay will facilitate minimally invasive assessment of ad patients in primary care settings and continuous monitoring of disease progression.

Transactions

Action Obligated Date
Amendment $0
Original award $291,692

Quick answers

Who received award R43AG080878?

R43AG080878 was awarded to Wellsim Biomedical Technologies Inc. by National Institute on Aging (National Institutes of Health) on September 21, 2022.

How much is award R43AG080878 worth?

$291,692 has been obligated on R43AG080878.

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