Project Grant R43AG076140
- Federal Project Grant Award Summary Viewmind Inc. received a $495,731 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) to evaluate its proprietary digital diagnostic technology for detecting Alzheimer's disease biomarkers in individuals with mild cognitive impairment (MCI). The award, issued September 20, 2025, with completion targeted for September 19, 2026, funds research to validate Viewmind's ocular digital phenotyping platform—which...
- This Project Grant award of $353,391.00, provided by the National Institute on Aging (CFDA 93.866 - Aging Research), aims to validate the use of a "Personal Learning Curve" paradigm as a sensitive marker of early memory decline related to Alzheimer's disease (AD) biomarkers in a large, diverse sample of older adults. The study seeks to determine if this digital cognitive assessment tool, which measures learning over repeated evaluations, can detect subtle AD-related memory failures...
- This $778,398 National Institute of Mental Health project grant will fund research at the University of California, San Diego to test the accuracy of eye tracking as an early screening tool for autism spectrum disorder (ASD) in the general pediatric population. The research aims to screen approximately 8,000 toddlers ages 12-24 months attending well-baby checkups over the five-year period from May 2023 to March 2028. Researchers will use eye tracking technology to measure social attention...
- The National Eye Institute (NEI) awarded a $295,766 Project Grant (CFDA 93.867 - Vision Research) to Ther-Ai LLC, located in Oviedo, FL, to develop a smartphone application called ILIGN. The goal of this project is to create a rapid, non-invasive, and accurate artificial intelligence-driven system to pre-screen for ocular misalignment (strabismus), a leading cause of preventable blindness in children. The expected outcome is a software platform that allows untrained end-users to diagnose...
- Summary of VIS4ION-FIT Federal Grant Award The National Eye Institute (NEI) awarded New York University School of Medicine a $1.5 million Project Grant under the Vision Research program (CFDA 93.867) on September 15, 2025, for the development and evaluation of VIS4ION-FIT, an artificial intelligence-enabled wearable and smartphone application designed to improve physical activity and health outcomes in persons with blindness or low vision (PBLV). The system leverages camera and sensor data...
- This three-year, $658,002 National Science Foundation Engineering project grant funds research at Florida Atlantic University investigating changes in cerebral and retinal blood flow responses as a potential early diagnosis mechanism for Alzheimer's disease. The goal is to establish a viable, cost-effective early detection strategy through eye imaging procedures and new optical technologies measuring eye and brain blood flow changes associated with Alzheimer's. Machine learning tools will...
- Grant Award Summary Advanced Brain Monitoring, Inc., a veteran-owned small business based in Carlsbad, California, received a $325,672 Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) awarded on September 16, 2025. The project, extending through May 31, 2027, focuses on validating and deploying a novel mobile electroencephalography (EEG) platform to objectively assess neurocognitive deficits...
- Federal Project Grant Award Summary Vanderbilt University Medical Center received a $659,026 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) awarded March 1, 2026, with a completion date of February 28, 2031. The project, "Imaging Soluble Amyloid Oligomer Flow Dynamics in the Eyes for Detection of Alzheimer's Disease," addresses early detection of Alzheimer's disease through development of a novel retinal imaging approach. The research team...
- Grant Summary: Activities4Care Digital Platform Plans4Care Inc. received a $490,262 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) awarded on June 15, 2025, with completion targeted for May 31, 2026. The award funds development and testing of Activities4Care, a digital platform designed to address the critical unmet need for meaningful activities among the 6+ million individuals living with Alzheimer's disease and Alzheimer's disease-related...
- This Project Grant award of $4,787,820.00 from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to gain a better understanding of the individual- and system-level characteristics that influence diagnosis of mild cognitive impairment (MCI) and Alzheimer's disease and related dementias (ADRD), and how diagnosis can moderate the effects of cognitive decline on employment, future care, and quality of life. The key objectives are to: 1) examine whether older adults experiencing...
ACCESSIBLE EYE TRACKING SOLUTION FOR ASSESSMENT OF COGNITIVE DEFICITS IN ALZHEIMER'S DISEASE - PROJECT SUMMARY MILLIONS OF AMERICANS CURRENTLY SUFFER FROM ALZHEIMER'S DISEASE, AND THE NUMBER IS EXPECTED TO ESCALATE RAPIDLY IN THE COMING YEARS. THE DISEASE PREVALENCE HAS A SIGNIFICANT FINANCIAL AND EMOTIONAL IMPACT ON FAMILIES, CAREGIVERS, AND THE HEALTHCARE SYSTEM AS A WHOLE. ALTHOUGH THERE IS CURRENTLY NO CURE FOR ALZHEIMER'S, EARLY DISEASE DETECTION AND DIAGNOSIS OF THE DISEASE CAN PROVIDE AN OPPORTUNITY FOR TREATMENT AND MANAGEMENT STRATEGIES TO ENHANCE QUALITY OF LIFE. CURRENT ASSESSMENT METHODS ARE EITHER INVASIVE, NON-OBJECTIVE, OR NOT AVAILABLE TO THE MASSES, AND THEREFORE FAIL TO MEET THE USE AND CAPABILITY REQUIREMENTS WE NEED. AN INDIVIDUAL'S EYE MOVEMENT QUALITY IS AN OBJECTIVE NEUROLOGICAL HEATH INDICATOR, BUT ASSESSMENT HAS BEEN LIMITED TO CLINICAL VISITS WITH SPECIALIZED EQUIPMENT AND TRAINING, AND THEREFORE HAS RECEIVED LIMITED ADOPTION. THIS PROJECT WILL REMOVE THOSE LIMITATIONS BY PRODUCING AN ASSESSMENT THAT WILL UTILIZE COMMONLY AVAILABLE MOBILE DEVICE HARDWARE AND REAL-TIME DATA ANALYSIS TO TRACK AND MEASURE EYE MOVEMENTS. THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP AN APPLICATION THAT UTILIZES INTEGRATED MOBILE DEVICE CAMERAS AND ALGORITHMS TO MEASURE EYE MOVEMENT THAT CAN BE USED TO ASSESS AND MONITOR AGE- AND ALZHEIMER'S DISEASE RELATED CONDITIONS. THE MEASURES FROM THE MOBILE APP WILL BE COMPARED TO A HARDWARE-BASED EYE TRACKING SYSTEM TO DETERMINE THE RELIABILITY AND VALIDITY OF THE MEASURES. SUCCESSFULLY COMPLETING THESE AIMS WILL RESULT IN AN ACCESSIBLE TOOL THAT CAN EFFECTIVELY ASSESS EYE MOVEMENT QUALITY. THE HIGH ACCESSIBILITY, DISTRIBUTION, AND USABILITY OF OUR APPLICATION WILL PROVIDE AN OPPORTUNITY FOR EARLY DETECTION, THERAPIES, AND AWARENESS OF ADDITIONAL MARKERS FOR THE MILLIONS THAT CURRENTLY ARE OR ARE EXPECTED TO SUFFER FROM ALZHEIMER'S DISEASE.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | ($14k) | 2/22/24 | ||
| Not listed | $497.2k | 9/14/22 | ||
| Not listed | $497.2k | 9/14/22 |