Project Grant R42NS097069

This $274,547 Project Grant awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program aims to develop a novel Aneurysm Sealing Device (ASD) for endovascular treatment of Abdominal Aortic Aneurysms (AAA). The project seeks to create a device that can completely seal the aneurysm sac, reducing the risk of post-procedure complications and the need for repeat interventions. Key objectives include validating the device's adaptability...

Endoshape, Inc. was awarded a $370,938 project grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to develop radiopaque shape memory polymers for neurovascular embolotherapy applications. The Cardiovascular Diseases Research program aims to support heart and vascular research, including through competitive research training grants. Under this award, Endoshape will develop new radiopaque shape memory polymer materials incorporated into embolic coils....

The National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the Department of Health and Human Services, awarded a $179,000 Project Grant under CFDA 93.286 "Discovery and Applied Research for Technological Innovations to Improve Human Health" to Brigham & Women's Hospital Inc. to develop image processing algorithms for improving the visualization and interpretation of digital subtraction angiography (DSA) imaging used for cerebrovascular surgical planning....

This $341,598 Project Grant awarded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286) aims to develop quantitative photoacoustic imaging techniques to characterize blood clots. The primary objectives are to: 1) Characterize the unique optical properties of biological chromophores relevant to thrombus formation, and 2) Develop algorithms to...

The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH), awarded a $287,000 Project Grant (CFDA 93.837 - Cardiovascular Diseases Research) to The Regents of the University of California, San Francisco (UCSF) to conduct research on photodynamic therapy (PDT) for treating abdominal aortic aneurysms (AAA). The project aims to investigate how PDT can enhance extracellular matrix (ECM) cross-linking and eliminate proliferating immune cells within the...

The University of California, Davis (UC Davis) was awarded a $161,000 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program. The project aims to develop a surgical probe prototype specifically designed for positron emission tomography (PET) radiotracers, with the goal of improving the ability to detect tumors and lymph nodes during...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is funding the development of an implantable device to improve vascular access and safety for hemodialysis patients. The $324,836 Phase I SBIR grant to Flowpoint Medical Inc. will be used to refine the manufacturability and operational parameters of a 3D-printed titanium device that guides the...

This $516,556 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program, funds the development and validation of a novel, personalized flow modeling paradigm for assessing the hemodynamics of the fetal aorta. The key objectives are to: (1) create a personalized flow modeling approach based on fetal echocardiography data to...

This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research (CFDA 93.837) program, provides $734,463 to The Methodist Hospital Research Institute (HMRI) to conduct a two-part research study focused on improving patient selection and treatment for peripheral artery disease (PAD). The first aim is to establish a novel MRI-histology anatomic scoring system that can predict technical failure of percutaneous vascular...

This $662,832 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports the development and demonstration of a Photoacoustic Visualizer (PAV) system by Actuated Medical, Inc. The PAV is intended to improve the accuracy of sacral nerve stimulation (SNS) lead placement for treating urinary and bowel incontinence. The three-phase project aims to design...