Project Grant R41OD039877
- This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $749,227 to the Trustees of Boston University for the acquisition of a three-photon microscopy system. The system will support fluorescence and phosphorescence lifetime imaging capabilities to enable researchers at the university's Neurophotonics Center to image intact brain tissue up to 1.2 mm in depth with sub-micron resolution. This state-of-the-art imaging...
- This National Science Foundation (NSF) Cooperative Agreement award under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $994,138 to Modendo Inc., a for-profit company located in Boulder, CO, to develop and validate a prototype ultrathin endomicroscope instrument for high-resolution, minimally invasive optical imaging of the brain in animal neuroscience research. The key innovation is achieving a cross-sectional area more than 10 times smaller than...
- This $450,173 federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will provide a new light-sheet microscopy system to the Seattle Children's Research Institute (SCRI), University of Washington (UW), and other partner institutions in the Seattle area. The goal is to enable biomedical researchers to image tissue structure from whole organism scale to microscopic resolution, supporting a diversity of basic and...
- This federal Project Grant award of $183,751 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will support research to develop a miniaturized ultra-widefield micro-camera array microscope (MCAM) capable of imaging a large area of the cerebellar cortex with cellular resolution in freely behaving mice. The goal is to enable recordings of cerebellar neuronal...
- This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $1,131,640 to the University of Southern California (USC) to acquire a new high-end multimodal multiphoton fluorescence microscope system. The purpose of this new microscope is to replace an aging system and bring currently non-existent advanced imaging capabilities to support a large user base across several key research areas at USC, including neuroscience,...
- The University of Minnesota was awarded a $3,972,414 Project Grant from the National Institute of Neurological Disorders and Stroke within the Department of Health and Human Services to develop an electro-optical multiphoton microscope. The microscope will leverage advances in electro-optical beam deflection to enable random-access multiphoton interrogation of neurons and synapses with sub-microsecond access times. This will allow neuroscientists to collect the simultaneous recordings needed...
- This federal Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) provides $942,983 to acquire a Bruker Luxendo TruLive3D light-sheet microscope system. The award, effective September 1, 2024 through August 31, 2025, will enable rapid 3D volumetric imaging of live specimens such as mouse, fly, and zebrafish embryos with high resolution and minimal phototoxicity. This advanced microscope system will benefit a user group of...
- This $738,752 Project Grant was awarded on May 1, 2025 by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) under CFDA 93.351 for Research Infrastructure Programs. The funding will be used by the University of Colorado Boulder to acquire an Evident Scientific (Olympus) SPINSR super-resolution spinning disk confocal microscope for the university's Porter Biosciences Light Microscopy Core Facility. The new microscope will replace and update the...
- The Project Grant award of $535,416 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) supports the development of a technological toolkit for noninvasive mapping of ionic activity in the mouse brain. The goal is to create a voltage-sensing nanoprobe using DNA nanoparticles, indocyanine green dye, and a quencher, which can provide high-resolution...
- This $325,000 Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) to the Texas A&M Engineering Experiment Station (Tees) aims to develop 3D-integrated micro-photometer chips that enable minimally invasive, long-term stable, and high-quality fluorescence recording in deep brain regions. The research will elucidate the effects of beam collimation, compact chip size, and mechanical flexibility of implantable optoelectronic probes on the quality of in...
This federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $416,925 to Objective Biotechnology, Inc. to develop and evaluate a miniature, high-performance microscope system for imaging brain activity in freely behaving mice. The award period runs from September 15, 2025 to August 31, 2027. The key objectives are to engineer the "Mini-MScope" device with a highly sensitive imaging sensor, evaluate its performance for imaging the cortex through an intact skull, and comprehensively assess its capabilities across diverse behavioral contexts. This innovation aims to enhance the commercial viability and facilitate wider adoption of the Mini-MScope technology for neuroscience research. The NIH ORIP program focuses on supporting advanced research instrumentation and infrastructure to strengthen biomedical research capabilities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $416.9k | 9/3/25 |