This federal Project Grant award for $586,525.00, awarded on August 15, 2024 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports the development of a non-invasive infrared light therapy and medical device to treat spinal cord injury. The primary research aims to attenuate the acute injury and inflammatory response in the initial 24 hours following spinal...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, aims to develop innovative magnetically responsive drug delivery electrospun fibers to improve regeneration after spinal cord injury (SCI). The total funding amount is $151,559.00 over the period from August 3, 2024 to July 31, 2026. The primary recipient, Rensselaer...
This $424,875.00 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund a comprehensive study of gene transcription patterns in diverse classes of neurons that connect the brain to the spinal cord after spinal cord injury in a mouse model. The research team at Marquette University will use single-cell sequencing technologies to profile...
This $391,250 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research aimed at developing effective therapeutic strategies for spinal cord injury (SCI) recovery. The key objectives are to: 1) Temporally regulate PTEN (phosphatase and tensin homolog) knockdown after SCI to promote axon regeneration while avoiding...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $184,837 to The Ohio State University to research a polymer-based drug delivery system for promoting spinal cord repair. The project aims to optimize the fabrication and characterization of microspheres containing the drug gabapentin to enable targeted intraspinal delivery,...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $234,949 to Yale University to conduct research on mechanisms that support raphespinal tract plasticity and regeneration after spinal cord injury. The objectives are to use anatomy, spatial transcriptomics, and intersectional in vivo chemogenetics to define the capacity and...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to understand the molecular mechanisms regulating axon regeneration after spinal cord injury. The $1,006,322 award to the University of California, San Diego will fund experiments using a novel patch-based single-cell RNA sequencing approach to refine a regeneration...
This $490,049 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research conducted by Shearit LLC to investigate the efficacy of their LAMIFLO drag reducing polymer treatment in reducing ischemic stroke damage. The project aims to demonstrate that LAMIFLO, when administered intravenously one hour after transient middle...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $397,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program to the Massachusetts Institute of Technology (MIT). The grant, effective May 1, 2025 through April 30, 2030, will support innovative research to study fundamental principles linking neurodevelopmental processes to the functional organization of neural circuits. The goal is to...
This $337,088 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) aims to establish a versatile platform for delivering RNA therapeutics specifically to the central nervous system (CNS). The project seeks to develop an innovative delivery system that integrates high-efficiency RNA encapsulation, precise cell targeting, and minimal cellular disruption. The key objectives are to engineer...