The National Institute of Mental Health (NIMH) awarded a $449,228 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Neuronexus Technologies, Inc. (doing business as Nuvectra) to develop an integrated system for long-term electrophysiological profiling of human brain organoids. The 2-year project, running from March 2025 to February 2027, aims to create a specialized biological assay chamber, high-fidelity 3D neural probes, and an integrated software system to...
This federal Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports the development of a novel multimodal microelectrode array (MEA) probe with integrated electrophysiological (ephys) recording and fast-scan cyclic voltammetry (FSCV) capabilities for high-density neuromodulator sensing. The $517,546 award to Trustees of Dartmouth College will enable the optimization, benchmarking, and validation of...
The federal Project Grant award R43MH135817, totaling $383,553.00, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The funding supports the development and enhancement of a novel, minimally invasive system and procedure for non-surgical placement of electroencephalogram (EEG) electrodes in mice. This technology enables faster, more cost-effective EEG measurements in freely moving mice, which is highly valuable for...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $659,217 to develop a novel neuropeptide Y (NPY)-sensitive microelectrode for continuous measurement of endogenous NPY release in brain tissue. The primary objective is to optimize an aptamer-modified platinum microelectrode to detect dynamic NPY concentrations as low as 2 pg/ml with high temporal resolution, enabling researchers to monitor NPY...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will fund the development of a new "mesoscopic electrophysiology" recording system to study brain function in non-human primates. The $606,548 award aims to create two fully functional mesoscopic electrophysiology systems, which will combine the large field of view...
This Small Business Innovation Research (SBIR) Phase I project, awarded by the National Science Foundation (NSF) under the TIP (Technology, Innovation, and Partnerships) program (CFDA 47.084), aims to develop a novel, multifunctional neural probe for advancing neuroscience research. The $254,456 grant awarded to Neurobionics Inc. on August 15, 2024, will fund the integration of electrical, optical, and chemical capabilities into a single implantable device. This versatile tool will enable...
The National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA 93.173 "Research Related to Deafness and Communication Disorders" program, awarded a $2,167,850 Project Grant to Spikegadgets, Inc. to commercialize a platform for large-scale chronic electrophysiology. The project aims to develop a compact 512-channel integrated circuit, known as the "eChip", to enable multi-electrode array (MEA) manufacturers to integrate electronics directly onto...
This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $427,500.00 to the University of Oregon to develop and validate scalable fabrication methods for high-density amorphous silicon carbide microelectrode arrays for chronic neural interfacing. The key goals are to refine the fabrication process for 128-channel ultra-microelectrode arrays and establish their performance in terms of single unit yield, stability, and tissue response in small animal...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will provide $2,565,783 to Oregon Health & Science University (OHSU) from September 1, 2023 to August 31, 2026 to develop novel genetically encoded sensors and actuators for monitoring and manipulating neuromodulatory signaling activities in the brain at the cellular and circuit levels. The project aims to enable large-scale in vivo...
Purdue University was awarded a $1,304,216 Project Grant by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) to develop and test a new platform for high-density 3D electrophysiology and two-photon calcium imaging in freely moving animals. The goal is to enable simultaneous recording of millisecond electrical dynamics and spatial mapping of neural circuit activity during natural behaviors to better understand how the brain processes...