Project Grant R41HL180172
- This $306,872 Project Grant award from the National Institute of Environmental Health Sciences (CFDA 93.113 - Environmental Health) supports Bioprinting Laboratories Inc. in Dallas, TX to develop a high-throughput developmental neurotoxicity (DNT) testing platform using engineered brain organoids. The key products and services to be delivered include: Establishing genetically engineered, induced pluripotent stem cells with a promoter-reporter assay system on a high-throughput, pillar/perfusion...
- The National Science Foundation awarded a $450,000 Project Grant to the George Washington University under the Engineering federal grant program (CFDA 47.041) to develop scalable heart-on-a-chip platforms. Over a three-year period from April 2022 through March 2025, the University will create automated systems integrating human heart slice culture components with sensor and actuator arrays. This will enable continuous on-chip multiparametric analysis of human cardiac physiology at the cellular...
- This $440,000 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research at Northwestern University to create an unbiased and global map of the cellular response to environmental proteotoxic stress. The project will integrate cutting-edge chemical-genetic screening with computational analysis to identify critical components, functions, and regulatory nodes in the proteostasis network that cells...
- This $563,468 federal project grant was awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) to Interlink Electronics, Inc., a for-profit company based in Irvine, California. The grant supports the development of a high-resolution, ground-level air quality monitoring system using hyper-local, low-cost sensor nodes and AI forecasting technologies. The project aims to create a truly low-cost sensor node to monitor...
- The federal Project Grant award of $507,000.00 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) aims to develop an automated system that integrates micro-electromechanical sensors, automation, and machine vision to simultaneously measure electrophysiological properties and contractile forces in single human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). This innovative system is expected to significantly reduce measurement time...
- This National Science Foundation (NSF) Engineering (CFDA 47.041) program grant, in the amount of $400,000, supports the development of a tissue-like, converged sensing platform for tracking excitation-contraction dynamics in cardiac organoids. The project aims to: Develop a scalable assembly strategy to fabricate an array of three-dimensional sensor structures using planar semiconducting graphene material, designed to detect both electrical and mechanical stimuli. Evaluate the multifunctional...
- This $100,000 Project Grant from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems supports the development of a 3D human stem cell cardiac model for cardiac electrophysiology medical device safety assessment. Funded under the NSF Engineering program (CFDA 47.041), this award will allow the University of Maryland, College Park to create a novel in vitro model for evaluating the safety and efficacy of cardiac medical devices through January...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), provides $303,165 to Amelia Technologies LLC, a woman-owned small business, to develop the SphereDNA platform. SphereDNA is a novel high-throughput screening approach that leverages microfluidic impedance cytometry to measure DNA damage, addressing the need for scalable and precise toxicity evaluation methods to assess the...
- This $5,453,538 Project Grant was awarded on September 15, 2025 by the National Institute of Environmental Health Sciences (NIEHS), which administers the Environmental Health federal grant program (CFDA 93.113). The grant was awarded to New York University School of Medicine to investigate the accumulation of micro- and nanoplastic particles in mammalian tissues, including human exposure pathways, tissue deposition, and potential health impacts. Key objectives include quantifying MNP...
- This $599,486 National Science Foundation award under the Engineering (47.041) program will fund the development of an engineered cardiac tissue model with embedded soft microelectronics for continuous cardiotoxicity screening at The Pennsylvania State University from January 2022 to September 2023. The key product is a 3D-bioprinted, microvascularized cardiac tissue model integrated with stretchable microelectronics to enable real-time, intra-tissue measurement of cardiotoxicity responses to...
The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $525,824 Project Grant to Neurolux Inc. in Northfield, IL. The grant aims to commercialize an Electromechanically Monitored Engineered Heart Tissue (EMEHT) platform developed at Northwestern University. Key deliverables include: 1) Developing a consumable electronics fabrication process to meet design criteria for high-throughput EMEHT studies, and 2) Designing and building custom data acquisition and bioamplification equipment with intuitive software to assess the EMEHT platform. The project will leverage the Fullenkamp Lab at Northwestern University as a testbed for the EMEHT platform. This award supports the advancement of non-animal models for evaluating therapeutics, as emphasized by the FDA, using human induced pluripotent stem cell-derived cardiomyocytes to gain insights into heart diseases and assess potential cardiac treatments.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $525.8k | 8/27/25 |