Microwave-enhanced microreactor for ultrafast detection of protein biomarkers

Ended Project Grant Awarded Last action

Award ID
R41GM146522
Recipient
Awarding agency
Obligated
$519,756

Award facts

Assistance listing
93.859 Biomedical Research and Research Training
Completion date
Originally
Place of performance
Fayetteville, AR 72701, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
In diagnosis, risk stratification, and management of life-threatening diseases/conditions, every minute counts and unambiguous detection of many relevant protein biomarkers is crucial. Unfortunately, the workflow of current unambiguous approach-mass spectrometry-is bottlenecked by the sample preparation process. A microwave-enhanced, flow-through microreactor is proposed here for both selective capture and digestion of proteins to address this major limitation. The specific aims of this phase I sttr are to create a prototype microreactor and to demonstrate a proof of concept of the microreactor-enabled mass spectrometry analysis of protein biomarkers. The proposed technology and product will streamline the workflow of mass spectrometry analysis of proteins, free end users from the laborious and tedious multiple sample preparation steps, and allow near real-time and unambiguous detection of protein biomarkers, as well as therapeutics, drug targets, etc.

Transactions

Action Obligated Date
Amendment $0
Amendment $259,878
Original award $259,878

Quick answers

Who received award R41GM146522?

R41GM146522 was awarded to VIC Foundry Inc. by National Institute of General Medical Sciences (National Institutes of Health) on September 1, 2022.

How much is award R41GM146522 worth?

$519,756 has been obligated on R41GM146522.

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