Multistage LC-MSN for automated glycan isomer assignment of glycopeptides - n- and o-linked glycosylation are some of the most common, abundant, and biologically important posttranslational…
Ended Project Grant Awarded Last action
- Award ID
- R41GM142363
- Recipient
-
Protein Metrics, LLC UEI D3ZDKNNU9PT9
- Awarding agency
-
National Institute of General Medical Sciences
National Institutes of Health, Department of Health and Human Services
- Obligated
- $769,710
Award facts
- Assistance listing
- 93.859 Biomedical Research and Research Training
- Completion date
- Funding
-
- $513,140.00 Federal
- $256,570.00 Non-federal
- Place of performance
- California, USA
Award details come from USAspending.gov.
Description
Multistage LC-MSN for automated glycan isomer assignment of glycopeptides - n- and o-linked glycosylation are some of the most common, abundant, and biologically important posttranslational modifications of proteins, yet they are also some of the most difficult to study. The dominant analytical platform for the study of glycosylation is mass spectrometry, yet this platform on its own is incomplete, because IT cannot elucidate glycan topology and linkage stereochemistry. This project will advance the use of mass spectrometry for glycan structure determination, especially for the case of o-linked glycans, by studying the ION propensities of various structural motifs in multi-stage ION trap mass spectrometry, and by building new software for structure inference from such mass spectra.
Transactions
| Action | Federal | Non-federal | Date |
|---|---|---|---|
| Amendment | $0 | $0 | |
| Amendment | $256,570 | $0 | |
| Original award | $256,570 | $256,570 |
Quick answers
Who received award R41GM142363?
R41GM142363 was awarded to Protein Metrics, LLC by National Institute of General Medical Sciences (National Institutes of Health) on April 16, 2021.
How much is award R41GM142363 worth?
$769,710 has been obligated on R41GM142363: $513,140 in federal funding and $256,570 in non-federal funding.
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