A normal paradigm to monitor perinatal asphyxia using a combined ultrasound-neuromodulation and photoacoustic-imaging device
Ended Project Grant Awarded Last action
- Award ID
- R41EB033751
- Recipient
-
Brimrose Technology Corp UEI WKDYRE26KLT7
- Awarding agency
-
National Institute of Biomedical Imaging and Bioenginering
National Institutes of Health, Department of Health and Human Services
- Obligated
- $600,000
Award facts
- Assistance listing
- 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health
- Completion date
- Originally
- Place of performance
- Maryland, USA
Award details come from USAspending.gov.
Description
- Abstract
- The brimrose technology corporation and partner, the johns hopkins university, propose using non-invasive ultrasound neuromodulation to identify hypoxic-ischemic encephalopathy (HIE) in newborns to reduce death and lifelong brain injury. HIE is the leading cause of neonatal death and impacts 2-6 of every 1,000 live births in the developed world. Our goal is to investigate and demonstrate the effect of graded hypoxia and repeated oxygen/glucose deprivation on neural response using ultrasound modulation. We will then develop and validate an ultrasound-neuromodulation coupled with photoacoustic-imaging device prototype to monitor neonatal brain injury. This device will be used for early diagnosis of HIE to enable timely intervention, which minimizes long-term disability. The two organizations have established a strong research team and joint operating lab at hopkins to develop this system. Due to various limitations of current methods, there is an urgent need for an early HIE diagnostic kit to enable prompt therapeutic interventions. There are no early diagnostic procedures or devices available in the clinic for HIE. Hence, our proposal addresses a critical unmet need.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $300,000 | |
| Original award | $300,000 |
Quick answers
Who received award R41EB033751?
R41EB033751 was awarded to Brimrose Technology Corp by National Institute of Biomedical Imaging and Bioenginering (National Institutes of Health) on September 23, 2022.
How much is award R41EB033751 worth?
$600,000 has been obligated on R41EB033751.
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