A biliary tract-specific fluorescence image-guided surgery
Ended Project Grant Awarded Last action
- Award ID
- R41EB032284
- Recipient
-
Optosurgical, LLC UEI N5FFBMLQHAJ9
- Awarding agency
-
National Institute of Biomedical Imaging and Bioenginering
National Institutes of Health, Department of Health and Human Services
- Obligated
- $768,996
Award facts
- Assistance listing
- 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health
- Completion date
- Originally
- Funding
-
- $512,416.70 Federal
- $256,579.00 Non-federal
- Place of performance
- Laurel, MD, USA
Award details come from USAspending.gov.
Description
- Abstract
- The primary liver cancer including intrahepatic bile duct cancer pose significant global burden of illness with increasing incidence and mortality in US and around the world. Surgery remains the most effective form of treatment. However, surgical complication rates for medium to high complexity hepatectomies persist in 30-40% range even in highly skilled hands and at high volume centers. The critical challenges appear to be attributable to navigating liver parenchymal dissection, where size of resection surface, associated with blood loss and missed bile leaks from the liver parenchyma, and prolonged operative time during dissection pose significant obstacle. In this research, we propose to develop an upgraded laparoscopic imager for deeper biliary-specific fluorescent imaging using a short-wave infrared (SWIR) sensor and high-definition RGB color vision, and to test the utility of our multimodal laparoscopic imaging technique in liver surgery throughout preclinical swine studies. The clear anatomic display of intrahepatic critical structures and functional physiology will make the hepatic dissection safer and more efficient for any liver resection. The goal of this 1-year research is to develop and evaluate the novel biliary-specific fluorescence and laparoscopic vision/display through the following specific aims; AIM1: to develop a formfactor SWIR camera system for fluorescence image-guided laparoscopy; aim 2: to validate the usefulness of the developed new vision platform in preclinical animal studies.
Transactions
| Action | Federal | Non-federal | Date |
|---|---|---|---|
| Amendment | -$741 | $0 | |
| Amendment | $0 | $0 | |
| Amendment | $0 | $0 | |
| Amendment | $256,579 | $0 | |
| Original award | $256,579 | $256,579 |
Quick answers
Who received award R41EB032284?
R41EB032284 was awarded to Optosurgical, LLC by National Institute of Biomedical Imaging and Bioenginering (National Institutes of Health) on September 23, 2021.
How much is award R41EB032284 worth?
$768,996 has been obligated on R41EB032284: $512,417 in federal funding and $256,579 in non-federal funding.
On GovTribe
See this award's full record
- Every transaction and subaward
- The recipient's other awards and teaming partners
- Similar grant awards
- Ask GovTribe AI about this award