Project Grant R41AR086074
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $679,995 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to Tennessee Technological University. The funding will support the development of an innovative self-powered smart piezoelectric total knee arthroplasty (TKA) implant platform that enables continuous in vivo measurement of joint kinematics and compartmental joint kinetics. This research aims to...
- This $548,828 Project Grant was awarded on September 21, 2023 by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant was awarded to Knoubis Bio Inc., a for-profit organization based in California, to support research on a non-immunosuppressive disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis. The project aims to develop a new therapeutic approach...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is developing the X-Visual, a sensor to track fracture healing in cannulated screws used for hip fracture fixation. The $299,999 award to Aravis Biotech LLC will cover the design, computational modeling, and initial testing of this innovative device that can non-invasively measure screw bending...
- This federal Project Grant award, valued at $306,722.00 and awarded on September 19, 2025, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The funding supports the development of a distal femoral fracture (DFF) fixation plate with an implantable, battery-free, wireless sensor to monitor fracture site strains. This technology aims to enable personalized,...
- This $628,174 Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports research to investigate the cellular origins and molecular mechanisms underlying arthrofibrosis, a debilitating fibrotic joint disorder. The research aims to address critical gaps in the understanding of arthrofibrosis pathogenesis, with the goal of developing new non-surgical,...
- This federal Project Grant award of $594,000.00, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), supports the research and development of a "Skin and Bone Integrated Pylon" (SBIP-3D) technology for direct skeletal attachment of limb prostheses. The project, conducted by Poly Orth International, aims to demonstrate the feasibility and benefits of this novel prosthetic attachment approach, which integrates the prosthesis directly with the...
- This $219,609 Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) aims to develop a method for assessing mechanical failure of bone matrix using in vitro cell cultures. The goal is to overcome the challenge of requiring large bone specimens to directly measure changes in bone matrix mechanical properties, which is a major roadblock to identifying factors...
- The federal Project Grant award R56AR082872 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The $395,171 award to Rush University Medical Center aims to determine the in vivo chemical changes of contemporary ultra-high molecular weight polyethylene (PE) tibial liners used in total knee arthroplasty (TKA) procedures, and how these changes impact wear behavior...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $296,256 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research Federal Grant Program (CFDA 93.846) to Advanced Molecular Healix Inc., a Small Disadvantaged Business located in Baltimore, Maryland. The grant aims to develop a novel therapeutic strategy for enhancing pedicle flap survival by increasing the expression of hypoxia-inducible factor-1 alpha (HIF-1α) mRNA. The research...
- This $158,555 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to develop a first-of-its-kind, personalized, wireless, electronic-free metamaterial interbody fusion cage that can precisely measure forces during spinal fusion in-vivo and transmit the data wirelessly in real-time. The award supports research to design and evaluate the packaged...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $306,871 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to Flex Orthopaedics, Inc. in Agoura Hills, CA. The objective of the research project is to develop a compliant intramedullary stem design that can increase the longevity of revision total knee arthroplasty (RTKA) implants. The proposed stem design aims to alleviate rotational constraint and reduce wear at the bone-implant interface, which are common failure modes for RTKA procedures. The project will optimize the stem design and conduct initial pre-clinical studies to support regulatory clearance and eventual clinical testing. The award period runs from September 2025 through August 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $306.9k | 9/11/25 |