Project Grant R35GM165588
Award Date 9/1/26
Completion Date 4/30/31
Dollars Obligated $381K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Ottawa Hills, OH 43606, USA
Similar Awards
- The National Institute of General Medical Sciences awarded the University of Rochester $448,196 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop synthetic tools for constructing carbon-nitrogen bonds using N-aryl and N-alkenyl nitrogen intermediates. The research targets the synthesis of nitrogen heterocycles, which are critical structural components in pharmaceuticals and natural products. The project will develop catalytic methods to...
- The National Institute of General Medical Sciences awarded $548,084 to the University of North Texas Research and Innovation Division on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop ruthenium(II)-catalyzed enantioselective functionalization of arene and alkene derivatives for asymmetric synthesis of natural products and complex organic molecules. The research targets enantioselective functionalization of ortho- and meta-aryl C-H bonds...
- The National Institute of General Medical Sciences awarded $149,264 to the University of California, Berkeley on February 8, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop site-selective iridium-catalyzed C-H borylation methods directed by noncovalent interactions. The research aims to create a systematic and tunable strategy for controlling site selectivity in C-H bond functionalization, enabling precise structural editing of bioactive compounds at...
- Federal Project Grant Summary The University of Toledo received a $559,543 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 5, 2025, with completion scheduled for August 31, 2028. This award supports fundamental biomedical research investigating the overlap between mitotic and ferroptotic cell death pathways through the development and characterization of novel hybrid small...
- The National Institute of General Medical Sciences awarded Michigan State University $335,924 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to engineer glycyl radical enzyme hydroalkylases for asymmetric C-C bond formation in pharmaceutical synthesis. The project develops biocatalytic methods to form C(sp3)–C(sp3) bonds stereoselectively from simple, achiral starting materials, addressing the synthesis of sp3-rich compounds needed for therapeutic...
- The National Institute of General Medical Sciences awarded The University of Texas Southwestern Medical Center $433,780 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop innovative chemical reactions for drug discovery. The funded research pursues two research directions. First, the recipient will develop stereoselective catalytic reactions to synthesize chiral N-heterocycles—sp3-rich scaffolds prevalent in FDA-approved drugs—using...
- The National Institute of General Medical Sciences, a component of the National Institutes of Health, awarded The University of Chicago $590,711 in project grant funding on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859). The funding supports development of new synthetic methods to accelerate preparation of diverse analogues for medicinal chemistry studies. Over the five-year performance period ending June 30, 2031, the research addresses carbon-carbon...
- The National Institute of General Medical Sciences awarded Michigan State University $413,244 in Project Grant R35GM165574 on August 1, 2026, supporting development of catalyst-controlled methylene insertion reactions and C-H functionalization methods to accelerate synthetic pharmaceutical chemistry and overcome bottlenecks in drug analog synthesis. The funded research advances two complementary synthetic platforms. The methylene insertion work applies metal catalysts—particularly iron...
- The National Institute of General Medical Sciences awarded the University of Oklahoma a Project Grant of $360,157 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop and apply sulfenylcarbenes and sulfenylnitrenes as reagents for site-selective chemical transformations in drug discovery. The research addresses the slowdown in pharmaceutical development by expanding chemical space through scaffold hopping—transforming established drug...
- The National Institute of General Medical Sciences awarded The Ohio State University $410,893 on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct genomics-accelerated discovery and biosynthesis research on phosphonic acid natural products. The project, identified as R35GM161629, runs through December 31, 2030, with performance at Columbus, Ohio. The research program aims to discover microbial natural products of chemotherapeutic value, establish...