Development of a patient-provider decision aid for HIV post-exposure prophylaxis

Ended Project Grant Awarded Last action

Award ID
R34MH129217
Recipient
Awarding agency
Obligated
$717,323

Award facts

Assistance listing
93.310 Trans-NIH Research Support
Completion date
Funding agency
Office of the Director National Institutes of Health, Department of Health and Human Services
Place of performance
State College, PA 16802, USA

Award details come from USAspending.gov.

Description

Abstract
While many questions remain regarding specific rates for HIV PEP preventable transmissions related to the real world challenges of HIV seroconversion and measuring risk, we do know that: 1) among individuals who experience a known exposure HIV PEP is effective and potentially cost saving if initiated in a timely manner and completed fully; 2) patients who have been offered, accepted, and even completed HIV PEP continue to report confusion and inaccurate information regarding its use; and 3) in many contexts decision aids have demonstrated improved patient knowledge regarding decision making, decreased decisional conflict, and improved patient-provider communication. Given these gaps, the long-term goal of this work is to develop, refine, and validate a technology-delivered patient-provider decision aid to assist providers in better understanding and effectively implementing HIV PEP in practice, and assist patients to better understand the decision they are making when provided with HIV PEP as an option so that they may more successfully 1) make the decision, and 2) complete the entire 28-day course of mediation when they decide to initiate HIV PEP. The proposed patient-provider decision aid leverages a known clinical opportunity to engage patients who are at risk for seroconversion in initiation of HIV PEP. By creating an internet-delivered multimedia tool that: 1) removes provider biases regarding what qualifies as an HIV risk from the discussion process; 2) slows the process of information sharing and decision making down and presents information in short, repeatable modules; and 3) incorporates an opportunity for patients to reflect on key priorities that have been shown to impact decision making and adherence (e.g. social support/stigma, HIV risk perception, cost/access, side effects) prior to making the decision we anticipate that patients will have less decisional conflict, feel more confident about their decision, and for patients who initiate HIV PEP, be more able to complete the entire 28- day regimen. Lastly, the proposal includes relationship building via a community advisory board to support all steps of the patient-provider decision aid development and subsequent testing. Principles of design justice (e.g. adopting CO-design methods, developing specific mechanisms for accountability, centering the needs of marginalized users) will be used to partner with this group of patient and health care providers to design aspects of intervention content, and plan details of the future efficacy testing study.

Transactions

Action Obligated Date
Amendment -$67,245
Amendment $67,245
Amendment $0
Amendment $234,297
Amendment $234,297
Amendment $0
Amendment $0
Amendment $248,729
Amendment $0
Amendment -$253,306
Amendment $253,306
Amendment -$253,306
Amendment -$253,306
Amendment $253,306
Original award $253,306
Show all 15

Subawards

Subrecipient Amount Awarded
University Of California, Davis Development of a patient-provider decision aid for HIV post-exposure prophylaxis $11,270
University Of California, Davis $0
District Of Columbia Forensic Nurse Examiners Development of a patient-provider decision aid for HIV post-exposure $0
University Of California, Davis Development of a patient-provider decision aid for HIV post-exposure prophylaxis $96,072
District Of Columbia Forensic Nurse Examiners Development of a patient-provider decision aid for HIV post-exposure $14,196
University Of California, Davis Development of a patient-provider decision aid for HIV post-exposure prophylaxis -$96,072
District Of Columbia Forensic Nurse Examiners Development of a patient-provider decision aid for HIV post-exposure -$14,196
District Of Columbia Forensic Nurse Examiners $28,392
University Of California, Davis Development of a patient-provider decision aid for HIV post-exposure prophylaxis $190,096

Quick answers

Who received award R34MH129217?

R34MH129217 was awarded to The Pennsylvania State University by National Institute of Mental Health (National Institutes of Health) on July 1, 2022.

How much is award R34MH129217 worth?

$717,323 has been obligated on R34MH129217.

Which agency awarded R34MH129217?

National Institute of Mental Health (National Institutes of Health) awarded R34MH129217, with funding from Office of the Director (National Institutes of Health).

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