Improving HIV care engagement among ugandan adolescent girls and young women through reductions in male partner alcohol use and intimate partner violence risk: the kisoboka mukwano intervention

Ended Project Grant Awarded Last action

Award ID
R34AA030489
Recipient
Awarding agency
Obligated
$880,510

Award facts

Assistance listing
93.273 Alcohol Research Programs
Completion date
Place of performance
Arizona, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
In uganda, adolescent girls and young women (agyw) are disproportionately affected by HIV and have poor viral suppression rates, increasing their risk of onward transmission. Intimate partner violence (IPV) is a major barrier to mitigating the impact of HIV among agyw. Agyw living with HIV (agywlhiv) in sub- saharan africa (SSA) who have experienced IPV have worse medication adherence, viral suppression, and care engagement than those without IPV. Further, male partner alcohol use directly and indirectly increases IPV risk among agyw in SSA. Thus, an intervention with components that address heavy alcohol use among male partners could decrease agyw's IPV risk, especially in uganda, which has the highest alcohol use per capita in SSA. Couples- based interventions have effectively reduced male partner alcohol use, relationship conflict IPV, and improved viral suppression and HIV care engagement; yet, none have been tailored to agywlhiv in SSA. We propose to develop and pilot a couples-based intervention that focuses on improving HIV care engagement and art adherence among agywlhiv by reducing heavy alcohol use among male partners and couple IPV risk. Additionally, we will explore the intervention's effects on agyw viral load for the additional key benefit of treatment as prevention. Our aims are to: 1) adapt the behavioral components of a brief MI-based alcohol intervention to create the proposed kisoboka mukwano ("IT is possible, my love!") intervention. The intervention will promote strategies for reductions in male partner alcohol use, coping with relationship conflict and stress, changing norms that reduce IPV and support engagement in HIV care and art adherence among agywlhiv, and, thereby, enhance future sustained viral suppression and benefits of treatment as prevention. The intervention will be adapted and tailored to be delivered with heterosexual couples, involve peer navigators, address IPV, and be developmentally appropriate for agywlhiv in uganda. We will develop and refine the intervention in collaboration with an intervention steering committee through: qualitative research with married/cohabiting agywlhiv, married/cohabiting men, and key informants and an initial pilot test with 6 couples. 2) we will assess safety, acceptability, feasibility, and preliminary estimates of the potential for the intervention, as compared to the control group, to improve HIV, alcohol, and IPV outcomes. We will examine preliminary effects on agyw HIV care engagement, agyw art adherence, heavy alcohol use among male partners, and couple IPV risk and explore effects on agyw viral load as well as intermediate outcomes related to intervention components. We will assess these outcomes at baseline and then at 3- and 6-month follow-up. Study findings will be used to guide a subsequent R01 proposal to test the intervention in a larger clinical trial.

Transactions

Action Obligated Date
Amendment -$372
Amendment $158,490
Amendment $238,120
Amendment $242,136
Original award $242,136

Subawards

Subrecipient Amount Awarded
Makerere University School Of Public Health Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women Through Reductions in Male Partner Alcohol Use and Intimate Partner Violence… $38,876
University Of California, San Diego $12,507
San Diego State University $47,627

Quick answers

Who received award R34AA030489?

R34AA030489 was awarded to Arizona State University by National Institute on Alcohol Abuse and Alcoholism (National Institutes of Health) on September 20, 2022.

How much is award R34AA030489 worth?

$880,510 has been obligated on R34AA030489.

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