Use of DVC® systems to acquire and remotely view data for improved monitoring of animal models and their environment
Ended Project Grant Awarded Last action
- Award ID
- R24OD037711
- Recipient
-
Research Foundation For Mental Hygiene, Inc. UEI EAL3QNJK3CB9
- Awarding agency
-
Aggregate Financial Assistance Data
National Institutes of Health, Department of Health and Human Services
- Obligated
- $349,729
Award facts
- Assistance listing
- 93.351 Research Infrastructure Programs
- Completion date
- Funding agency
- Office of the Director National Institutes of Health, Department of Health and Human Services
- Place of performance
- New York, USA
Award details come from USAspending.gov.
Description
- Abstract
- This application requests funds to acquire specialized laboratory mouse housing systems- digital ventilated caging (DVC) designed to initiate a new generation of husbandry, breeding colony and animal welfare management, and research data acquisition. The requested equipment will improve NKI's animal housing by establishing an ability for 24-hour remote monitoring of the cage microenvironment, promoting health, less disturbance of cage inhabitants, and normal baseline behavior and physiology, conditions necessary to produce more accurate animal models in brain-and-behavior studies. Such models, which, at NKI, aim at understanding the molecular basis of normal and diseased states, also have improved translational usefulness, including the development of early diagnostic and treatment abilities. Long-term monitoring of the behavior and activity of mice in their natural environment using non-intrusive methods in their home cages can better reveal their behavior and activity in their natural environment. Using home cage monitoring devices to track the activity levels of mice, researchers can evaluate phenotypic expression of inserted or deleted genes as well as the effectiveness of interventions, such as exercise and pharmaceutical treatments, on activity levels and all while improving overall general health and husbandry. The DVC systems, as a shared resource, will be used to provide GEM (genetically modified mice) models for multiple studies supported by funding from the NIH, alzheimer's association, jerome lejeune foundation, new vision research, the DR. Ralph and marian falk medical research trust, and the templeton world charity foundation. Upgrading and modernizing animal caging systems along with continued institutional funding for facility improvements further the NKI animal care and use program toward aaalac accreditation.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | -$0 | |
| Original award | $349,729 |
Quick answers
Who received award R24OD037711?
R24OD037711 was awarded to Research Foundation For Mental Hygiene, Inc. by Aggregate Financial Assistance Data (National Institutes of Health) on September 15, 2024.
How much is award R24OD037711 worth?
$349,729 has been obligated on R24OD037711.
Which agency awarded R24OD037711?
Aggregate Financial Assistance Data (National Institutes of Health) awarded R24OD037711, with funding from Office of the Director (National Institutes of Health).
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