Project Grant R24OD037633
- This $778,241 Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will support the development, characterization, and validation of recombinant antibodies and antibody-based biosensors for the zebrafish research community. The project aims to address the lack of reliable, reproducible, and molecularly defined antibodies for zebrafish proteins, which has hindered mechanistic cell biological and biochemical studies using this...
- This Project Grant award, valued at $722,774 and provided by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) under CFDA 93.351, aims to develop a new resource system to provide individual zebrafish research laboratories with decentralized capabilities for reproducible sperm cryopreservation and quality management. The project's goal is to address the urgent need to transition from the centralized sperm cryopreservation approach at the Zebrafish...
- This federal Project Grant award of $779,657, funded by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351 - Research Infrastructure Programs), aims to establish and expand community-accessible resources for site-directed transgenesis in zebrafish. The University of Colorado-Denver will replace existing Tol2-based transgenes with engineered PhiC31 integrase genomic loci (PIGLET) to create the first universal landing site strains for zebrafish,...
- This $3.63 million Project Grant from the Department of Health and Human Services National Institutes of Health Office of the Director, under the Trans-NIH Research Support program (CFDA 93.310), will fund research at Duke University from August 2022 through July 2025 to develop predictive dynamic models of the functional connectivity underlying visually guided behavior in zebrafish. Using integrated optical imaging, optogenetic manipulation, and recurrent neural network techniques, the...
- This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351 - Research Infrastructure Programs) provides $194,375 to the University of Wisconsin-Madison to develop robust genome editing tools for generating floxed alleles and editing amino acid changes in the zebrafish model system. The project aims to establish a synthetic exon-mediated integration approach to reliably introduce loxP sites into target genes, enabling...
- The University of Mississippi was awarded a $132,062 Project Grant by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) to acquire a state-of-the-art zebrafish housing and breeding system for the university's aquatics facility. The goal is to support the expanding use of zebrafish, a critical model organism, in biomedical research at the university. The award will fund the implementation of new zebrafish culture systems, including single-sided and...
- This $114,458 Project Grant was awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Duke University. The grant supports quantitative research into how zebrafish appendages regenerate original size and function after injury. Specifically, the research aims to dissect how zebrafish tissue encodes "size memory" during appendage regeneration and how signaling dynamics in...
- This $173,434 Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will support the modernization and expansion of the recirculating zebrafish tanks and monitoring equipment at the University of New Mexico (UNM) Castetter Hall Animal Resource Facility. Specifically, the funding will be used to purchase: 1) six new recirculating zebrafish racks with upgraded pumps and remote monitoring capabilities, 2) upgrades to three existing...
- The Department of Health and Human Services (HHS) National Institutes of Health (NIH) awarded a $1,319,060 Project Grant to Duke University under the Trans-NIH Research Support (CFDA 93.310) program. The grant, effective September 1, 2023 through August 31, 2026, will fund research to study the robust formation of organs, with a focus on the development of the semicircular canals in the inner ear of zebrafish. The research aims to measure variations in tissue patterns, investigate the respective...
- This $616,841 project grant was awarded by the National Institute of Child Health and Human Development (NICHD), under the CFDA program "Child Health and Human Development Extramural Research", to Yale University beginning on August 15, 2025 and scheduled for completion on April 30, 2030. The project aims to investigate the molecular mechanisms that regulate genome activation and gene expression during embryonic development in vertebrates, with a focus on understanding how specific...
This Project Grant award of $863,982 from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will support the development of an integrative 3D microanatomical and gene expression atlas for the zebrafish model organism. The goal is to create a comprehensive resource that will facilitate the interpretation of multi-omic data in the context of whole-organism biology and developmental stages. Key deliverables include a 3D whole-animal lifespan atlas based on advanced imaging techniques such as microCT and histotomography, which will anchor 2D histological and gene expression data. This will provide researchers with facile access to detailed, subcellular-resolution data on normal and abnormal phenotypes in zebrafish. The project involves a multidisciplinary team with expertise in histology, microscopy, imaging, and genomics. The award period runs from August 15, 2025 to July 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | ($42k) | 8/25/25 | ||
| Not listed | $0 | 8/6/25 | ||
| Not listed | $906.4k | 8/4/25 |