Project Grant R24GM137748

This Project Grant award of $532,947 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will fund the development and validation of a unified, cloud-based data processing workflow and database called LC-BINBASE for high-resolution LC-MS/MS metabolomics and lipidomics data. The goal is to create a standardized and reproducible metabolomics data processing system that can be used across different laboratories and mass...

This Project Grant award, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to advance the field of native mass spectrometry (MS) analysis. The $316,825 award, effective May 1, 2025 through April 30, 2026, supports the development of an innovative intact mass deconvolution method designed to improve the speed, accuracy, and user-friendliness of proteins and nucleic acid molecular weight...

The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859), awarded a $1,469,739 Project Grant to the Research Foundation of the City University of New York (RFCUNY) to purchase a TIMSTOF-FLEX MALDI-2 high-resolution mass spectrometer. This advanced instrumentation will support biomedical research projects across 12 laboratories from CUNY and nearby institutions, focusing on areas such as conformational dynamics of...

The National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) awarded a $750,000 Project Grant (CFDA 93.351) to The Ohio State University to permanently acquire a Bruker timsTOF Flex MALDI-2 quadrupole time-of-flight mass spectrometer. This advanced imaging mass spectrometer will empower NIH-funded investigators at Ohio State and Case Western Reserve University in their tissue imaging studies, providing three critical new capabilities: MALDI-2 post-ionization,...

This $1,574,994 Project Grant awarded by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will fund the acquisition of a high-resolution tandem mass spectrometer to support large molecule structural characterization research at the University of California, Los Angeles (UCLA). The state-of-the-art mass spectrometer, equipped with electrospray ionization and various activation/dissociation methods, will enable advanced analysis of a broad range of...

This $1,077,584 Project Grant award from the National Institutes of Health (NIH) Research Infrastructure Programs (CFDA 93.351) will fund the purchase of a Bruker timsTOF HT mass spectrometer and supporting liquid chromatography equipment for the Center for Advanced Proteomics Research (CAPR) at Rutgers University-Newark. The new mass spectrometry system will enable CAPR to significantly expand its proteomics research capabilities and support a major user group of 15 NIH-funded investigators...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA Program 93.859 Biomedical Research and Research Training provides $311,168 to Accelerated Muscle Biotechnologies Consultants, L.L.C. to develop infrastructure and capabilities for myocardial and skeletal muscle imaging using synchrotron radiation at the Brookhaven National Labs facility. The key objectives are to: 1) acquire muscle small-angle X-ray scattering (MYSAXS) data comparable to current...

The National Institutes of Health (NIH) awarded a Project Grant under the Research Infrastructure Programs (CFDA 93.351) to Baylor College of Medicine for $597,985 to acquire a QTRAP 7500 hybrid triple quadrupole/linear ion trap mass spectrometer system. This state-of-the-art ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) instrumentation will expand the bioanalytical capacity of Baylor's Texas Children's Microbiome Center Metabolomics and Proteomics Mass...

This Project Grant award of $316,012, provided by the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351), will fund the acquisition of an Iridia 1kHz excimer laser ablation (LA) system for the Boston University Center for Biometallomics (CBM). The new state-of-the-art LA instrument will enable ultrafast, high-resolution multi-elemental mapping of clinical and preclinical biospecimens using hyphenated laser ablation-inductively coupled plasma...

The National Institutes of Health (NIH) awarded a $1,352,820 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to the Massachusetts General Hospital (MGH) to acquire a novel high-throughput and high-sensitivity mass spectrometer called the Orbitrap Astral. This state-of-the-art instrument will be used to conduct proteomic research focused on cancer and Alzheimer's disease at MGH. The Orbitrap Astral's unprecedented speed and sensitivity are expected to enable new...