Project Grant R24AI198135
- Federal Grant Award Summary Rhode Island Hospital received a $1.73 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded September 24, 2025, with an ultimate completion date of August 31, 2030. The award funds a randomized controlled trial (RCT) evaluating treatment modalities to halt the progression of schistosomiasis-related hepatic fibrosis in Uganda. The research will...
- Federal Project Grant Award Summary The University of New Mexico received a $430,251 Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 18, 2025, with a completion date of May 31, 2027. This award supports fine-resolution genetic mapping research utilizing advanced intercross lines of Biomphalaria glabrata, a primary snail vector for Schistosoma mansoni. The project employs double...
- Federal Grant Award Summary The University of Washington's Office of Sponsored Programs received a $273,875 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 1, 2026, with completion scheduled for April 30, 2028. The project develops a vessel-on-a-chip platform to investigate schistosome egg-induced endothelial remodeling and macrophage polarization in response to parasitic...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Whitehead Institute for Biomedical Research $899,850 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 20, 2026, with a completion date of January 31, 2031. This Project Grant supports fundamental research investigating host cell invasion mechanisms in apicomplexan parasites, including Toxoplasma and Plasmodium species. The research deliverables...
- Federal Project Grant Summary Award Information: The National Institute of Allergy and Infectious Diseases (NIAID) awarded $899,741 to Scripps Research Institute through the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 1, 2026, with a completion date of March 31, 2031. Products and Services: Under this five-year Project Grant, Scripps Research Institute will develop a long-acting injectable (LAI) therapy for hepatitis B virus (HBV) in individuals co-infected with human...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $777,360 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2030. This award funds research titled "Advancing Lymphatic Filariasis Elimination with Parasite Genomic Epidemiology," which will deliver comprehensive genomic analysis and characterization of Wuchereria bancrofti...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $633,218 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective July 17, 2025, with a completion date of June 30, 2030. This research grant funds a comprehensive investigation into Plasmodium falciparum Niemann-Pick C1-Related Protein 1 (PfNCR1), a cholesterol transporter located at the interface between the...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $228,000 to the University of Georgia Research Foundation through the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 1, 2026, for a two-year project concluding June 30, 2028. The award funds the development of parasite glycosylphosphatidylinositol (GPI) libraries to advance parasitic disease research and drug development. The project will establish an enzymatic...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant of $107,542 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period September 1, 2025, through August 31, 2027. The award supports investigator-initiated biomedical research examining the differential sorting and trafficking mechanisms of Plasmodium falciparum secreted proteins, with particular focus on how...
- Federal Project Grant Award Summary Seattle Children's Research Institute received a $696,562 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 5, 2026, with completion targeted for April 30, 2031. This award funds molecular and functional dissection of a divergent mRNA (messenger ribonucleic acid) export pathway in trypanosomatids, a group of parasitic protozoans. The...
The Biomedical Research Institute (BRI), operating as the Schistosomiasis Resource Center (SRC), received a $1.8M Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the five-year period from July 1, 2026, through June 30, 2031. The SRC provides no-cost research reagents and technical support to the global scientific community, including live Schistosoma parasites (three medically important species: S. haematobium, S. japonicum, and S. mansoni), infected laboratory hosts (rodents and snails), and life cycle stage materials (eggs and miracidia). In 2024, the facility supplied reagents to over 50 investigators worldwide, significantly reducing the financial and labor burden of parasite propagation for individual research institutions. The grant supports three primary objectives: continuing propagation of multiple Schistosoma species for reagent distribution to researchers, converting Biomphalaria glabrata (NMRI) snail production to a recirculating aquaria system to improve operational efficiency, and expanding access to viable life cycle stages for research purposes. Additionally, the SRC maintains a specialized repository of praziquantel (PZQ) and oxamniquine-resistant S. mansoni parasite lines, providing critical resources for ongoing studies examining new drug candidates against schistosomiasis—a parasitic disease affecting over 200 million people globally for which PZQ remains the only widely available anthelmintic treatment.Summary of Federal Project Grant Award
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.8m | 6/26/26 |