Project Grant R21MH142950
- Federal Project Grant Award Summary Emma Pendleton Bradley Hospital received a $368,500 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), effective May 1, 2026 through April 30, 2028. The award supports a two-year research study investigating the relationship between mitochondrial signaling, psychosocial stress, sleep disturbances, and internalizing disorders in children ages 9-12. The research employs cell-free...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded Massachusetts General Hospital a five-year Mentored Research Scientist Development Award totaling $182,851 under the Mental Health Research Grants program (CFDA 93.242), effective September 19, 2025, through August 31, 2030. This project grant supports research to identify deficient memory replay as a potentially treatable mechanism underlying impaired sleep-dependent memory consolidation (SDMC) in schizophrenia...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $197,578 Project Grant to Massachusetts General Hospital (The General Hospital Corporation) effective June 1, 2026, through May 31, 2031, under the Mental Health Research Grants program (CFDA 93.242). This K23 mentored career development award funds an intensive longitudinal study investigating sleep and circadian timing irregularities as short-term risk factors for adolescent suicide. The research will...
- Federal Project Grant Award Summary Award Details: The National Institute of Mental Health (NIMH) awarded a $704,700 Project Grant under CFDA 93.242 (Mental Health Research Grants) to Pennsylvania State University, operating as Penn State Milton S. Hershey Medical Center, on May 22, 2026. The award extends through April 30, 2029, and supports research addressing sleep and circadian dysfunction in autistic adolescents and young adults (AYA), ages 12-25. Deliverables and Research Objectives: The...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The University of Southern Mississippi a $116,247 Project Grant effective October 5, 2025, under the Mental Health Research Grants program (CFDA 93.242) to conduct a mixed-methods investigation into novel determinants of introspective accuracy and confidence in schizophrenia-spectrum disorders (SSDs). The research will examine relationships between objective sleep quality, introspective accuracy (the ability of...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded the University of Wisconsin–Madison a $427,625 Project Grant under the Mental Health Research Grants program (CFDA 93.242) effective April 1, 2026, through March 31, 2028. This award supports research investigating the use of temporal interference transcranial electric stimulation (TI-TES) to enhance sleep spindle activity in healthy subjects, with the goal of establishing foundational evidence for treating...
- Federal Grant Award Summary The Feinstein Institutes for Medical Research received $845,163 in project grant funding from the National Institute of Mental Health under the Mental Health Research Grants program (CFDA 93.242), awarded August 1, 2025, with completion targeted for May 31, 2030. The project, titled "Vital Signs for Psychosis: Personalized Longitudinal Markers of Psychosis Severity Using Automated Speech and Language Analysis," develops objective, low-cost clinical markers...
- Federal Grant Award Summary Emma Pendleton Bradley Hospital received a $164,516 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective October 1, 2025, through September 30, 2026. The award supports longitudinal research investigating developmental trajectories of pediatric irritability from early childhood through late adolescence, with emphasis on establishing...
- Federal Grant Award Summary Emma Pendleton Bradley Hospital received a $7,940,991 Project Grant from the National Institutes of Health (NIH) Office of the Director under the Construction Support program (CFDA 93.352) to construct and equip the Bradley Hospital Integrative Research Laboratories. Awarded September 15, 2025, with completion targeted for May 31, 2030, this initiative will deliver a new 13,856 square-foot research facility on Bradley Hospital's East Providence, Rhode Island campus....
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $1,004,971 Project Grant to the University of Pittsburgh on April 8, 2026, under CFDA 93.242 (Mental Health Research Grants) to develop an integrated platform for measuring and analyzing brain activity, cognitive states, behavior, and physiology in real-world settings. The research addresses a critical gap in neuroscientific knowledge by investigating dynamic interactions between brain function,...
Emma Pendleton Bradley Hospital received a $398,669 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), effective July 1, 2026 through June 30, 2028. The award funds a deep phenotyping study investigating daily fluctuations in psychosis-spectrum (PS) symptoms, sleep characteristics, and psychological stress in adolescents aged 14-17 years (N=40). Over a three-week sampling period, researchers will measure PS symptoms including hallucinations and paranoia, subjective stress ratings, and objectively measured sleep characteristics at both behavioral levels (actigraphy-estimated sleep duration, fragmentation, efficiency, timing, rhythmicity, and regularity) and biological levels (polysomnography/electroencephalography-indexed sleep spindle density, amplitude, and duration). The research addresses critical gaps in understanding the relationship between sleep disruption and psychosis-spectrum conditions in youth, a population at high risk for conversion to schizophrenia and lifelong mental illness. Rather than relying solely on correlational analyses, this study employs dense sampling across days to understand temporal fluctuations and mechanistic pathways, while simultaneously measuring co-occurring stress processes that may mediate or moderate the sleep-psychosis relationship. Findings are intended to inform treatment development for adolescents experiencing psychosis-spectrum symptoms and clinical high-risk presentations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $398.7k | 7/1/26 |