Project Grant R21MH140170
- Federal Project Grant Award Summary Emma Pendleton Bradley Hospital received a $164,516 project grant awarded on October 1, 2025, through the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award supports a one-year research study concluding September 30, 2026, examining pediatric irritability across developmental stages from early childhood through late adolescence. The research leverages...
- Federal Project Grant Award Summary Emma Pendleton Bradley Hospital received a $7.94 million Project Grant from the National Institutes of Health (NIH) Office of the Director under the Construction Support program (CFDA 93.352) to construct the Bradley Hospital Integrative Research Laboratories. The award, obligated on September 15, 2025, with a completion date of May 31, 2030, funds the development of a 13,856 square-foot state-of-the-art pediatric psychiatry research facility on the hospital's...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded $394,200 to the Research Foundation For Mental Hygiene, Inc. (through its New York State Psychiatric Institute division) under the Mental Health Research Grants program (CFDA 93.242) on August 1, 2025, for a five-year project period extending through July 31, 2030. This Project Grant funds a clinical research study examining the role of the anterior hippocampus in major depressive disorder (MDD) pathogenesis....
- Federal Grant Award Summary Children's Hospital Los Angeles received a $769,500 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on March 15, 2026, with a completion date of March 14, 2029. This three-year research initiative focuses on developing and evaluating Cognitive Behavioral Therapy for Depression in Autistic Youth (CBT-DAY), an autism-adapted therapeutic intervention designed to address the...
- Federal Grant Award Summary Cincinnati Children's Hospital Medical Center received a $820,196 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded March 5, 2026, with a completion date of February 28, 2031. This five-year research initiative investigates the impact of circadian misalignment on adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD) through observational and mechanistic studies...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Feinstein Institutes for Medical Research a Project Grant of $519,558 under the Mental Health Research Grants program (CFDA 93.242), effective June 15, 2025 through April 30, 2030. The research project focuses on identifying and validating cerebellar-cortical circuitry biomarkers as predictive indicators of antipsychotic treatment response in first-episode psychosis patients. The primary deliverables...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded a $154,880 Project Grant to the University of Virginia under the Mental Health Research Grants program (CFDA 93.242) for the period September 28, 2025 through September 27, 2028. The research project, titled "Epigenetic Biomarker Status, Negative Valence, and HPA-Axis Dysregulation: Mechanisms Underlying Risk for Postpartum Depression," investigates the biological mechanisms linking identified epigenetic...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Broad Institute of MIT and Harvard a $475,388 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to conduct basic neuroscience research investigating the transcriptional and neuro-immune consequences of KDM5B loss in bipolar disorder (BD). The award, initiated June 16, 2025, and extending through June 15, 2027, supports a two-year research initiative examining how genetic...
- Federal Grant Award Summary The Feinstein Institutes for Medical Research received a $1,659,568 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded June 2, 2025, with completion targeted for May 31, 2030. The award funds the ESPRITO EPINET project, which aims to expand a learning health system (LHS) framework for improving treatment outcomes in early first-episode psychosis (FEP) care. The project will enroll an...
- Federal Grant Award Summary Miresource, Inc. received a $627,600 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded on September 12, 2025, with completion targeted for March 14, 2026. The project, in partnership with the nonprofit Child Mind Institute (CMI), aims to develop an integrated software solution for longitudinal mental health monitoring that generates personalized clinical guides and facilitates...
Emma Pendleton Bradley Hospital received a $368,500 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), effective May 1, 2026 through April 30, 2028. The research project, "Mitochondrial Signaling, Stress, and Sleep in Children with Internalizing Disorders," investigates the relationship between psychosocial stress, mitochondrial dysfunction, sleep disturbances, and psychiatric symptoms in children. The study will recruit 60 children ages 9-12 with internalizing disorders from the hospital's day hospital program and collect baseline assessments from both children and caregivers regarding cumulative stress history, sleep disturbances, and behavioral health outcomes. The primary research products and services delivered through this award include the quantification and analysis of cell-free mitochondrial DNA (CF-mtDNA) as a novel biomarker of stress and psychiatric symptoms in pediatric populations. Researchers will utilize saliva-based CF-mtDNA measurement to examine the dynamic effects of psychosocial stress on mitochondrial function and circadian rhythm disruption. This research aims to advance understanding of the physiological mechanisms linking childhood stress to internalizing disorders and may identify mitochondrial signaling as a potential intervention target for improving mental health outcomes in youth.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 5/12/26 | ||
| Not listed | $368.5k | 4/28/26 |