Project Grant R21HS019527

Federal Project Grant Summary Greenmark Biomedical Inc. received a $270,594 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) for the period of September 1, 2025 through August 31, 2026. The project focuses on developing nano-fluorapatite (NFA) particles to restore non-cavitated carious lesions in tooth enamel. Rather than relying on traditional remineralization approaches, this...

Federal Grant Award Summary Periomics Care LLC received a $297,711 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), awarded on August 6, 2025, with a completion date of July 31, 2026. This Phase I research project focuses on developing zinc tetraammine difluoride (ZAF), a novel precursor compound that generates nanocrystals for caries arrest and remineralization. The research seeks to...

Grant Award Summary The National Institute of Dental and Craniofacial Research awarded The RAND Corporation a Project Grant of $728,647 on September 17, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121) to examine the impact of Medicaid Accountable Care Organizations (ACOs) on children's oral health outcomes and access to dental care. The primary deliverables include construction of a unique statewide dataset integrating patient, insurance, clinician, and...

Cooperative Agreement Summary Wake Forest University Health Sciences received a $681,331 Cooperative Agreement award dated August 14, 2025, from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) to conduct a clinical trial testing an intensive preventive dental intervention delivered within oncology practices. The primary product of this award is a clinical research study titled "Effectiveness of an...

Federal Grant Award Summary New York University received a $322,000 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), awarded July 15, 2025, with completion anticipated by July 14, 2027. This R03 award supports secondary data analysis of the CARIEDAWAY longitudinal pragmatic randomized trial to advance school-based caries prevention implementation. The project will conduct detailed...

Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded The Ohio State University a Project Grant of $693,179 on August 11, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121) to conduct a multistage mixed-methods study examining silver diamine fluoride (SDF) and Medicaid policy impacts on pediatric oral health. The project, which extends through May 31, 2030, will analyze national Medicaid data and conduct qualitative...

Federal Grant Award Summary The University of Florida's Division of Sponsored Research received a $639,248 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), effective June 1, 2025 through May 31, 2027. The award supports statistical methodology development and secondary analyses of national dental health data to assess marginal associations between dental caries and periodontal diseases. The...

Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded The Ohio State University a $645,988 Project Grant effective August 13, 2025, through August 12, 2027, under the Oral Diseases and Disorders Research program (CFDA 93.121). This research initiative, led by a multi-principal investigator team comprising a clinical pediatric dentist and basic science microbiologist, investigates the role of bacteriophages (viruses that infect bacteria) in...

Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded The Regents of the University of California, San Francisco a $451,000 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) on April 8, 2025, with completion scheduled for March 31, 2027. This research initiative investigates the effects of the oral microbiome on adverse outcomes in pediatric hematopoietic cell transplant (HCT) recipients, specifically examining the...

The University of Florida received a $511,706 Project Grant award dated August 19, 2025, from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121). The three-year study, concluding July 31, 2027, conducts a secondary analysis of data from an ongoing prospective randomized controlled trial involving 168 racially diverse preterm very low birth weight (VLBW) infants to evaluate whether frequent standardized oral care...