The National Heart, Lung, and Blood Institute (NHLBI) awarded a $100,050 Project Grant (CFDA 93.837 Cardiovascular Diseases Research) to the Cleveland VA Medical Research & Education Foundation to investigate the potential of cardiometabolic drugs and bariatric surgery to reduce the burden of atrial fibrillation (AF). The two-year project will leverage the Veteran Affairs electronic health records to perform comparative effectiveness research on the use of glucagon-like peptide 1 receptor agonists, sodium-glucose cotransporter-2 inhibitors, and metformin alongside bariatric surgery for secondary prevention of AF. The goal is to generate insights that could inform the design of future pragmatic clinical trials focused on managing cardiometabolic risk factors to improve outcomes for patients with pre-existing AF.
Generated 2/25/25, 2:45 AM