Project Grant R21ES038306
- The National Institutes of Health National Cancer Institute awarded Cincinnati Children's Hospital Medical Center $694,182 on June 1, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a prospective longitudinal cohort study examining biomarker levels and respiratory health effects associated with exposure to electronic cigarettes and combustible cigarettes in young children. The research enrolls 300 children ages 1 to 10 years across three equal exposure...
- The National Institute of Environmental Health Sciences awarded Wayne State University $473,313 on September 3, 2026, under the Environmental Health program (CFDA 93.113) to investigate how acid, base, and salt components of electronic cigarettes affect fetal lung development and immune function during pregnancy. The project examines sex-specific impacts of e-cigarette aerosols on neonatal respiratory health using a preclinical pregnant rat model with a state-of-the-art vaping system that...
- The National Institutes of Health awarded Health Research, Inc. (Roswell Park Division) $830,722 on August 15, 2026, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) to assess the respiratory effects of inhaling synthetic coolants used as flavor ingredients in electronic nicotine delivery systems. The project will evaluate pulmonary function and inflammatory effects resulting from inhalation of the synthetic coolants WS-3 and WS-23, which...
- This Project Grant award, valued at $282,862 and awarded by the National Science Foundation (NSF) under the Integrative Activities program (CFDA 47.083), supports research at Oklahoma State University (OSU) to investigate the health risks of e-cigarettes and cannabis aerosols, particularly those containing unregulated synthetic cooling agents. The key objectives of this 2-year project are to: (1) quantify exposure and toxicity levels of various vaping aerosol components, (2) assess variability...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded $821,294 to The Trustees of Columbia University in the City of New York on September 1, 2026, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077, Project Grant R01HL179303). The award funds the VAPESCAN study, a longitudinal investigation examining early lung toxicity associated with e-cigarette versus cigarette use in young adults aged 18–50....
- The National Heart, Lung, and Blood Institute awarded The Leland Stanford Junior University $718,824 in project grant funding (R01HL188006) on August 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837). The award funds research into the mechanisms by which electronic cigarette exposure drives vascular injury and atherosclerosis progression through the glutamate N-methyl-D-aspartate receptor (NMDAR) pathway in vascular smooth muscle cells. The research comprises three...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded Health Research, Inc. Roswell Park Division (doing business as Health Research At Roswell Park) $867,448 under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) on August 1, 2026. The recipient will conduct research assessing whether use of fruit-flavored electronic nicotine delivery systems (ENDS) relates to smoking reductions in people who smoke...
- The National Heart Lung and Blood Institute awarded $827,439 to Lundquist Institute For Biomedical Innovation At Harbor-UCLA Medical Center on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate mechanisms by which perinatal nicotine vaping exposure dysregulates pulmonary group 2 innate lymphoid cells (ILC2s) and promotes allergic asthma development in offspring. The research employs electronic nicotine delivery system (ENDS) exposure models and...
- The National Institutes of Health Office of the Director awarded The Ohio State University $773,576 on August 1, 2026, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) to conduct research on oral nicotine pouches and their abuse liability. The research will investigate how freebase nicotine fraction and moisture content in oral nicotine pouches affect the speed of nicotine delivery to users and how acute laboratory measures of abuse...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $317,000 Project Grant to The Research Foundation For The State University of New York (Stony Brook University) on August 7, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121). This two-year research initiative, concluding August 6, 2027, focuses on chemoprevention strategies for oral squamous cell carcinoma (OSCC) promoted by electronic cigarette exposure. The...
The National Institute of Environmental Health Sciences awarded $448,686 to the Research Institute At Nationwide Children's Hospital on September 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate how electronic cigarette vapor affects formation of intracellular bacterial communities and recurrence of otitis media caused by nontypeable Haemophilus influenzae. The research examines the molecular mechanisms through which passive exposure to e-cigarette aerosol and nicotine enhances bacterial invasion, persistence, and disease recurrence in the middle ear. Specific work includes determining the effect of e-cigarette combustion products and nicotine on middle ear epithelial cell function and intracellular bacterial community formation, with the aim of clarifying host-pathogen interactions and environmental exposures that drive otitis media sequelae to inform novel therapeutic approaches. The project addresses a gap in understanding how e-cigarette utilization affects susceptibility to otitis media in children, particularly as adolescent nicotine use through e-cigarettes has increased and the contribution of aerosol and nicotine exposure to inflammation, infection susceptibility, and fibrosis remains unclear. Performance occurs in Columbus, Ohio with an ultimate completion date of August 31, 2028. This is a Project Grant, an assistance type supporting discrete research projects with defined objectives.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $448.7k | 8/31/26 |