Project Grant R21DE034099
Award Date
6/17/25
Completion Date
6/16/27
Dollars Obligated
$450K
Federal Agency
National Institute of Dental and Craniofacial Research
Federal Grant Program
93.121
Assistance Type
Project Grant
Place of Performance
Texas, USA
Similar Awards
This federal Project Grant award, provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), aims to evaluate a telehealth-delivered adaptive intervention that promotes continuous positive airway pressure (CPAP) adherence and improves health outcomes for adults newly diagnosed with obstructive sleep apnea (OSA). The $1,415,112 award will fund a research study to compare the effects of motivational enhancement, device...
This federal Project Grant award of $332,862.00 from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research (CFDA 93.837) program, will support research to assess night-to-night variability in novel sleep disordered breathing severity metrics and their impact on daytime functioning. The study aims to characterize reliable biomarkers of obstructive sleep apnea (OSA) severity, as the current standard measure (Apnea-Hypopnea Index) underestimates...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will provide $688,800.00 to the University of Chicago to investigate the role of obstructive sleep apnea (OSA) in glycemic dysregulation among adults with type 1 diabetes. The research study aims to determine how OSA impacts glycemic control in this population and examine the underlying...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), part of the Cardiovascular Diseases Research program (CFDA 93.837), provides $711,226 to the University of California, Los Angeles (UCLA) to conduct research on the impacts of obstructive sleep apnea (OSA) on the brain. The objectives are to: 1) examine regional brain temperatures in OSA patients compared to controls; 2) assess whole-brain metabolite and antioxidant levels in OSA and controls; 3)...
This $740,271 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) supports research to assess the prevalence of undiagnosed obstructive sleep apnea (OSA) in primary care clinics, identify barriers to OSA diagnosis, and develop predictive tools for OSA risk and subtypes. The principal investigators are from The Ohio State University and the University of Pennsylvania. The sub-award to the University of...
This National Heart, Lung, and Blood Institute (NHLBI) funded Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) seeks to develop a novel 3D dynamic MRI (3D-DMRI) scheme to quantify airway collapse in patients with obstructive sleep apnea (OSA). The $426,717 award from August 2024 to May 2029 will be used by The University of Iowa to systematically validate the 3D-DMRI approach and assess its clinical utility for characterizing patterns of airway collapse, both in the...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), part of the Oral Diseases and Disorders Research program (CFDA 93.121), is funding the development of a medical device development tool (MDDT) in the form of an accelerated fatigue test calibrated by clinical data. The goal is to create a tool that can accurately predict the clinical performance and service life of resin composite dental restorations, in order to help accelerate the translation of...
This $135,000 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) will fund the ADA Forsyth Institute's "Forsyth Student Scholars Summer Internships in Oral Health Research" program. The program aims to increase the diversity of students from underrepresented and educationally disadvantaged groups entering the oral health research field. Key program activities include a mentored...
This $222,500 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will support research at The Children's Hospital of Philadelphia (CHOP) to investigate the pathogenic mechanisms of temporomandibular joint (TMJ) osteophyte formation. The key objectives are to test whether conditional ablation of the gene EXT1, which is involved in heparan sulfate synthesis, causes osteophyte formation...
The federal Project Grant award for "MICROMANAGING HUMAN SLEEP PHYSIOLOGY TO TREAT SLEEP APNEA AND OTHER DISORDERS" was provided by the National Institutes of Health (NIH) through the Trans-NIH Research Support program (CFDA 93.310). The $1,120,000.00 award to Northwestern University, a private research institution, will fund a 5-year research project focused on advancing scientific understanding of human sleep physiology and developing new approaches to treat sleep apnea and related...