Project Grant R21DC022365
- This Project Grant award of $427,625 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The objective is to establish the posterior lateral line (PLL) ganglion of larval zebrafish as a model system for studying neuronal repair and replacement in the inner ear. The researchers aim to determine the contributions of neural precursor cell populations to ongoing...
- This federal Project Grant award of $432,000 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The project, titled "The Mechanisms of Odorant Receptor Map Formation in Mice", aims to use advanced sequencing techniques to map the identity of all ~3,000 glomeruli in the juvenile mouse olfactory bulb and elucidate the mechanisms of olfactory map formation...
- This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), will provide $434,411 to Brandeis University to conduct research on the mechanisms of chemosensory neuron cilia regeneration. The goal is to identify the sensors, transducers, and effectors that drive the regrowth and restoration of function in sensory neuron cilia, which play a critical role in...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $387,500.00 to The Johns Hopkins University from January 1, 2025 to November 30, 2029 to elucidate the gene regulatory networks that control hair cell regeneration in zebrafish. The research aims to identify key transcription factors, such as SOX and SIX, that regulate the transition of support cells to a progenitor state capable of...
- This $536,617 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research conducted by Oregon Health & Science University (OHSU) to understand the mechanisms of adult neural regeneration using planarian and zebrafish model organisms. The research aims to elucidate how adult stem cells can generate the appropriate diversity of...
- This $113,541 Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research to investigate the cellular basis of odor-related memory formation and retrieval in the hippocampus of mice. The principal investigator at the University of Colorado-Denver will employ holographic stimulation techniques to study the properties and interactions of...
- This $270,000 project grant, awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to define the inherent regenerative capacity of the zebrafish spinal cord. The research seeks to understand the molecular signals that enable or inhibit spinal cord regeneration, with the goal of shifting the mammalian spinal cord injury response from scarring to regeneration. The work, to be...
- This federal Project Grant award for $486,750.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program. The grant supports research to explore the morphological changes and cell polarity mechanisms in supporting cells of the inner ear, which play a critical role in auditory function. The primary awardee, the Jackson Laboratory, a nonprofit biomedical research...
- This federal Project Grant award of $650,049, provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research aimed at understanding the neural basis of olfactory sensation. The project, conducted by researchers at Duke University, investigates the structural determinants and in vivo function of three mouse odorant receptors, including how receptor activation...
- This federal Project Grant award of $688,796 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The grant supports research focused on understanding how the olfactory (smell) system transforms odor information into perception, with the goal of characterizing the serial transformation of odor representations from receptors to the cortex. The project aims to provide...
This Project Grant award of $495,000 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD), which administers the Research Related to Deafness and Communication Disorders federal grant program (CFDA 93.173). The funding will support research to investigate the cellular dynamics and mechanisms underlying brain regeneration in zebrafish, with a focus on regeneration of specialized neurons called mitral cells in the olfactory bulb. The research aims to provide new insights into the robustness and neuronal plasticity of the olfactory system during regeneration, as well as define the molecular basis for mitral cell regeneration in zebrafish. This work has the potential to advance understanding of regenerative capacity in the context of brain injury and inform future research into treatments for neural disorders in humans. The award period runs from Aug 1, 2025 to Jul 31, 2027 and the research will be conducted by the Morgridge Institute for Research, Inc., a non-profit research organization in Wisconsin.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $495.0k | 7/29/25 |