This Project Grant award of $515,632 from the National Cancer Institute's (NCI) Cancer Cause and Prevention Research program (CFDA 93.393) supports research to prepare the U.S. and state governments for the potential implementation of two cigarette product standards by the FDA - a menthol ban and a nicotine reduction standard. The key objectives are to: 1) Estimate for each U.S. state the increase in people who smoke that would quit and enroll in quit lines following the implementation of...
This federal Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) totaling $885,824 aims to assess consumer response to smokeless tobacco modified risk marketing orders. The research activities will explore 1) consumers' exposure and reactions to authorized smokeless tobacco modified risk tobacco product (MRTP) claims, and 2) whether the MRTP claims influence smokeless tobacco demand and sensory evaluations. The project will be conducted...
The federal Project Grant award R21CA292195 was provided by the National Cancer Institute (NCI), which administers the Cancer Cause and Prevention Research (CFDA 93.393) program. The $226,504 award will fund a 2-year study to examine tobacco use behaviors and related mechanisms among U.S. adults and youth representing minority and intersecting minority identities, such as racial/ethnic minorities, sexual/gender minorities, low socioeconomic status, and rural populations. The research aims to...
This $1,389,542 Project Grant award from the National Institute on Minority Health and Health Disparities (CFDA 93.307 Minority Health and Health Disparities Research program) aims to evaluate population-based strategies for improving smoking cessation among rural populations. The key products and services to be delivered include: A randomized controlled trial (n=544) to determine the efficacy of providing a free nicotine replacement therapy (NRT) starter kit, along with digital NRT education,...
This $773,359 federal Project Grant award, funded by the National Institutes of Health (NIH) under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077), will support a randomized controlled trial to evaluate the effectiveness of nicotine pouches as a cigarette substitute. The University of Wisconsin-Madison will conduct this 5-year research study to assess how readily smokers will adopt nicotine pouches, how effectively pouches can substitute for...
The National Institutes of Health (NIH) Office of the Director awarded a $1,197,896 Project Grant under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) to the University of Oklahoma Health Sciences Center. The objective of this 5-year longitudinal study is to use traditional survey methods combined with ecological momentary assessment (EMA) to better understand the impact of electronic nicotine delivery system (ENDS) product characteristics on...
This Project Grant award of $622,957 from the National Institutes of Health (NIH) Office of the Director, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077), supports research by Duke University to investigate the chemical composition and behavioral effects of novel tobacco products, including oral nicotine pouches and "non-menthol" cigarettes. The study aims to analyze the flavors, sweeteners, and nicotine forms in these products, and...
This federal Project Grant award of $619,175 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) supports a Type 1 hybrid effectiveness-implementation trial to evaluate a novel harm reduction approach for oncology outpatients who smoke but refuse traditional tobacco treatment. The study will directly compare rates of switching from cigarettes to e-cigarettes against standard care, while also assessing key barriers and facilitators to implementation. The...
This $3,230,000 Project Grant awarded by the National Institutes of Health (NIH) Office of the Director under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) supports research to investigate the cardiovascular effects of dual use of tobacco and nicotine delivery products, such as cigarettes and e-cigarettes. The project, awarded to the University of California, San Francisco (UCSF), aims to: (1) understand the cardiovascular health effects of...
This federal Project Grant award of $370,000 from the National Institutes of Health (NIH) Office of the Director under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) will fund research by Marshall University Research Corporation (MURC) to determine the impact of synthetic coolants on nicotine's abuse liability and initiation-related behaviors. The goal is to utilize a novel vapor self-administration assay in mice to directly link...
SIMULATING THE IMPACT OF A MENTHOL BAN IN THE US; TRANSLATING THE CANADIAN MODEL - PROJECT SUMMARY MENTHOL CIGARETTES COMPRISE A SUBSTANTIAL PORTION OF THE AMERICAN CIGARETTE MARKET WITH PREVALENCE ESTIMATES REACHING ABOUT 35% (FTC, 2016). MENTHOL IS A FLAVOURING AGENT ADDED TO CIGARETTES THAT MASKS THE TASTE OF TOBACCO, INDUCES SENSORY EFFECTS, AND RECRUITS AND RETAINS SMOKERS. AFTER A THOROUGH LITERATURE REVIEW, A U.S. FOOD AND DRUG ADMINISTRATION (FDA) ADVISORY COMMITTEE NOTED THAT BANNING MENTHOL CIGARETTES WOULD BENEFIT PUBLIC HEALTH AND ANNOUNCED INTENTIONS TO REGULATE THE SALE OF MENTHOL IN TOBACCO IN NOVEMBER 2019. HOWEVER, IN ORDER TO REGULATE MENTHOL CIGARETTES, THE FDA REQUIRES EVIDENCE ON THE EXPECTED IMPACT OF REGULATING MENTHOL AND REAL WORLD KNOWLEDGE ON THE PROCESS OF IMPLEMENTATION. THIS STUDY WILL USE TWO NIH/TRS FUNDED LONGITUDINAL STUDIES, THE PATH IN THE US, AND A COHORT OF SMOKERS FROM ONTARIO, CANADA TO DEVELOP A SIMULATION MODEL PREDICTING HOW THE CANADIAN BAN, ONE OF THE ONLY EVALUATED NATIONAL LEVEL IMPLEMENTED MENTHOL BAN IN THE WORLD, WOULD BE REFLECTED IN THE US GIVEN DIFFERENCES IN AGE, SEX, RACE, MENTHOL USE, AND EXPECTATIONS OF CHANGE OF BEHAVIOUR. THE GOAL OF THIS PROJECT IS TO ESTIMATES OF THE IMPACT OF THE CANADIAN MENTHOL BAN TO PREDICT THE IMPACT OF MENTHOL REGULATIONS IN THE US ON SMOKING CESSATION, HEALTH OUTCOMES, AND HEALTH COSTS.