Project Grant R21AI196816
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $855,113 Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop passive immunotherapy interventions for measles virus infection. The research encompasses two primary objectives: (1) production and selection of neutralizing anti-fusion (anti-F) protein...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $923,708 to the La Jolla Institute for Immunology under the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 1, 2026, for a five-year project period concluding March 31, 2031. The grant funds the development of a therapeutic monoclonal antibody (MAb) cocktail targeting New World arenaviruses, specifically Machupo and Junin viruses, which cause hemorrhagic fever....
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Albert Einstein College of Medicine a $1.69 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 6, 2025, with completion scheduled for May 31, 2030. This award supports the development of human monoclonal antibodies (mAbs) as broad-spectrum immunotherapeutics for alphavirus infections, including Chikungunya virus, Mayaro virus, and...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3.56 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to J. David Gladstone Institutes on September 26, 2025, to support research through August 31, 2029. This grant funds the development and validation of a hybrid messenger RNA (mRNA) vaccine technology designed to elicit broadly neutralizing antibodies (bnAbs) against HIV-1. The primary...
- Federal Grant Award Summary Albert Einstein College of Medicine received a $231,000 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 1, 2026, for completion by May 31, 2028. The research focuses on developing human monoclonal antibodies (MAbs) targeting Herpes Simplex Virus (HSV) infections, with emphasis on antibody-dependent cellular cytotoxicity (ADCC) as the primary...
- Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $475,339 to Icahn School of Medicine at Mount Sinai under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a Project Grant commencing April 1, 2026 and concluding March 31, 2028. The award funds development and testing of peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) as therapeutic agents against Nipah virus (NIV), a highly lethal zoonotic paramyxovirus....
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded La Jolla Institute for Immunology a $279,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026, through March 31, 2028. Under this award, the Institute will conduct detailed analysis of antibody repertoires from 23 multiply-exposed individuals in the Democratic Republic of the Congo who demonstrate extraordinarily broad and strong...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $451,000 Project Grant to the University of Chicago effective June 17, 2025, through May 31, 2027, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award funds investigator-initiated biomedical research focused on understanding how retroviruses, specifically Mouse Mammary Tumor Virus (MMTV), manipulate antibody responses and evade host protective immunity. The...
- Summary of Federal Project Grant Award The National Institute of Allergy and Infectious Diseases (NIAID) awarded $159,300 to La Jolla Institute for Immunology on April 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support investigator-initiated research on human upper airway immune memory kinetics and durability against respiratory pathogens. The research project, which extends through March 31, 2031, focuses on characterizing upper airway immune cell...
- Federal Project Grant Award Summary New York University School of Medicine received a $466,125 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2027. The award funds research to elucidate the molecular mechanisms of orthopoxvirus entry, specifically examining the critical initial interactions between viral and human cellular proteins...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $279,000 Project Grant to the La Jolla Institute for Immunology on May 15, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research program, concluding April 30, 2028, focuses on developing panels of human monoclonal antibodies (mAbs) against mumps virus surface glycoproteins HN and F derived from both vaccinated and naturally infected individuals. The project will characterize the human humoral immune response to mumps virus, identifying which antibody epitope target sites provide the broadest viral genotype recognition, particularly between vaccine-derived genotype A and the currently circulating genotype G strain. The deliverables from this research initiative include comprehensive characterization of human antibody responses against mumps virus, identification of protective epitopes on viral surface proteins, and generation of monoclonal antibody panels that may be incorporated into post-exposure prophylaxis treatments and vaccine booster formulations. These products directly address critical gaps in understanding mumps immunity and support public health efforts to improve vaccine effectiveness and outbreak response capabilities, given recent breakthrough infections and hospitalizations among vaccinated populations.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $279.0k | 5/19/26 |