Project Grant R21AI196315
- Federal Project Grant Summary Award Details: Weill Medical College of Cornell University received a $442,146 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 6, 2026, with completion targeted for January 31, 2028. Products and Services: The award funds research to quantify, validate, and elucidate the mechanisms by which salicylate-based compounds potentiate bedaquiline's...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Weill Medical College of Cornell University a $2.94 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 23, 2025, with a completion date of June 30, 2029. This research initiative aims to advance understanding of resistance and tolerance mechanisms to nitroimidazole antibiotics (pretomanid and delamanid) in Mycobacterium tuberculosis, the...
- Federal Project Grant Award Summary Albany Medical College received a $451,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 6, 2026, through January 31, 2028. The grant funds investigator-initiated biomedical research examining the role of the Wnt/β-catenin signaling pathway in alveolar epithelial repair during tuberculosis (TB) infection and its regulation by...
- Federal Project Grant Award Summary Cornell University's Office of Sponsored Programs received a $746,602 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025 through July 31, 2030. The award supports investigator-initiated biomedical research to develop novel therapeutics for tuberculosis (TB) treatment by stimulating bacterial cyclic adenosine monophosphate...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3.18 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Sloan-Kettering Institute for Cancer Research, effective January 28, 2026, with a completion date of December 31, 2029. This research initiative focuses on investigating chalkophore-mediated respiratory oxidase flexibility and its role in Mycobacterium tuberculosis virulence. The...
- Federal Project Grant Award Summary Award Details: The National Institute of Allergy and Infectious Diseases (NIAID) awarded Weill Medical College of Cornell University a Project Grant valued at $254,250 under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award was obligated on August 7, 2025, with an ultimate completion date of July 31, 2027, and performance conducted in New York. Products and Services: The grant funds research to develop and test proteolysis-targeting...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston University Medical Campus a Project Grant totaling $245,250 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 9, 2026 through January 31, 2028. This investigator-initiated research grant supports a two-year study examining the mechanisms of alternative macrophage activation in pulmonary tuberculosis (TB), specifically investigating the phenotypes...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Trudeau Institute Inc. a Project Grant of $921,320 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective January 28, 2026, with completion targeted for December 31, 2030. The grant funds research to optimize antitubercular compounds targeting a novel Mycobacterium tuberculosis (MTB) protein, alanine aminotransferase ASPC. The project aims to advance a drug...
- Federal Project Grant Award Summary Albert Einstein College of Medicine received an $850,711 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on August 1, 2025, with a completion date of July 31, 2030. The grant supports research to develop non-sputum-based point-of-care tests (POCTs) for tuberculosis (TB) detection in resource-limited settings, addressing a World Health...
- Federal Grant Award Summary Weill Medical College of Cornell University received a $211,875 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 20, 2026, with completion scheduled for January 31, 2028. The grant funds research to develop and analyze conditional knockdown mutants of Mycobacterium tuberculosis (MTB) in C3HEB/FEJ mice that more closely replicate human...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded Health Research, Inc.'s Wadsworth Center Division a $403,756 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 14, 2026, for completion by March 31, 2028. This research initiative focuses on mapping the determinants of bedaquiline (BDQ) resistance in Mycobacterium tuberculosis (MTB), an extensively drug-resistant pathogen. The project delivers a comprehensive database of mutations in the mmpR gene (RV0678) that confer BDQ resistance through saturating mutagenesis techniques, enabling rapid diagnosis of resistance in clinical isolates via whole-genome or amplicon sequencing methodologies. The primary deliverables include development of a loss-of-function mutation database linked to BDQ resistance phenotypes and validation of this database's predictive accuracy against clinical MTB isolates. These products will support integration of BDQ resistance profiling into existing genetic analysis pipelines, improving diagnostic capabilities for clinicians treating drug-resistant tuberculosis. The research conducted at the Albany, New York facility addresses a critical gap in antimycobacterial drug resistance diagnostics, where BDQ resistance cannot currently be inferred directly from genetic sequencing data as readily as other anti-tuberculosis drug resistances.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $403.8k | 4/14/26 |