Development of a direct diagnostic test for infectious and congenital syphilis

Active Project Grant Awarded Last action

Award ID
R21AI186005
Recipient
Awarding agency
Obligated
$443,486

Award facts

Assistance listing
93.855 Allergy and Infectious Diseases Research
Completion date 74% complete
Originally
Place of performance
2323 Riverside Dr., Ottawa, ON K1H 1A1, Canada

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Current diagnostic tests for syphilis are non-optimal, in that they cannot differentiate active from past infection, cannot diagnose congenital syphilis, and have low sensitivity in early and late disease. With the number of infectious and congenital syphilis cases rapidly expanding in the US and worldwide, curbing the spread of disease will be aided by development of a better diagnostic test that is definitive, easily interpreted, and compatible with a point-of-care test format. In this research application we propose to develop a direct syphilis diagnostic test that: (1) exhibits high sensitivity and specificity at all disease stages; (2) can differentiate active versus past infections; (3) can differentiate syphilis from yaws; (4) can allow accurate disease staging; and (5) can be adapted to a point-of-care format for ease of testing in remote areas.

Transactions

Action Obligated Date
Amendment $0
Amendment $16,000
Amendment $16,000
Amendment $75,363
Amendment $75,363
Original award $260,760

Quick answers

Who received award R21AI186005?

R21AI186005 was awarded to University Of Victoria by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on August 9, 2024.

How much is award R21AI186005 worth?

$443,486 has been obligated on R21AI186005.

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