Project Grant R21AI182898
- Federal Project Grant Award Summary Eastern Washington University received a $470,978 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective April 9, 2026, with completion anticipated by March 31, 2029. The grant funds basic biochemical research focused on characterizing DAHP (3-deoxy-D-arabino-heptulosonate 7-phosphate) synthases in Pseudomonas aeruginosa, a highly...
- Federal Grant Award Summary The University of Washington received a $445,338 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on July 23, 2025, with a completion date of June 30, 2027. This award supports research investigating the mechanisms of age-related lung inflammation in pulmonary melioidosis, a frequently fatal tropical infection caused by Burkholderia pseudomallei. The...
- Federal Project Grant Award Summary Washington State University received a $497,779 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 17, 2026, with completion scheduled for January 31, 2031. The grant funds biomedical research investigating the role of FN-14 (fibroblast growth factor-inducible 14) receptor in tumor necrosis factor-alpha (TNF-α)-induced inflammation and...
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Washington $273,875 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on May 1, 2026, with completion targeted for April 30, 2028. The project delivers a vessel-on-a-chip platform technology designed to study schistosome egg-induced endothelial remodeling and macrophage polarization in a three-dimensional microenvironment that mimics human vascular...
- Federal Project Grant Award Summary George Washington University received a $444,920 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 1, 2025, through August 31, 2030. This award funds investigator-initiated biomedical research designed to elucidate the role of endogenous retroviruses (ERVs) in the development of type 2-dominated allergic inflammation in the lungs,...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a $777,360 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2030. This award funds research titled "Advancing Lymphatic Filariasis Elimination with Parasite Genomic Epidemiology," which will deliver comprehensive genomic analysis and characterization of Wuchereria bancrofti...
- Federal Grant Award Summary The University of Washington received a $188,760 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 1, 2025, through August 31, 2030. This award supports investigator-initiated biomedical research examining interferon gamma (IFNG)-dependent immunity to Mycobacterium tuberculosis (MTB), with focus on how lung macrophages regulate...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Washington a Project Grant totaling $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 10, 2026, with a completion date of June 30, 2028. This research initiative focuses on evaluating fusidic acid as a therapeutic option for treating drug-resistant Mycoplasma genitalium, a sexually transmitted bacterial pathogen with increasing prevalence...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $414,305 to the University of Washington (awarded February 19, 2026, with completion by January 31, 2028) under the Allergy and Infectious Diseases Research program (CFDA 93.855). This Project Grant supports structural and functional research on influenza virus neuraminidase (NA), a critical surface glycoprotein that enables viral infection, transmission, and propagation. The research...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded George Washington University a Project Grant of $444,125 on February 3, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct basic biomedical research on genetic determinants of host immunity to helminth infections. The research will be conducted through January 31, 2028, at the University's Washington, DC campus. The project aims to identify and...
Eastern Washington University received a $168,554 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 9, 2026, with completion targeted for June 30, 2028. The grant supports basic biomedical research investigating the role of the glucocorticoid receptor in phagocyte pro-inflammatory responses. The research addresses a critical gap in understanding how endogenous cortisol-glucocorticoid receptor signaling regulates macrophage and neutrophil responses to pathogens, with implications for developing safer glucocorticoid therapies that balance immunosuppression with preservation of host immune defense against opportunistic infections. The research utilizes larval zebrafish as the model organism, leveraging their optical and genetic accessibility to investigate molecular mechanisms modulating dynamic host-pathogen interactions in a live organism. The study examines how glucocorticoid receptor activation affects macrophage- and neutrophil-mediated clearance of fungal-derived pathogens, providing mechanistic insights that could inform the design of next-generation glucocorticoid therapeutics with improved safety profiles for patients requiring prolonged immunosuppressive treatment.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $168.6k | 7/9/26 |