Project Grant R21AI124797

The National Institutes of Health's National Institute of Allergy and Infectious Diseases awarded a $2.3 million Project Grant to the University of California, Davis to fund research targeting CD4 T follicular helper cells for enhancing HIV vaccine-induced humoral immunity. The two-year award, issued on May 12, 2021 under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support preclinical studies in rhesus macaques to better understand the immunological mechanisms...

This federal Project Grant award of $318,554.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research at Valparaiso University to investigate the regulation of chloride-driven fluid secretion and its subversion by the fungal pathogen Candida albicans. The key objectives of this 3-year research project are to: 1) determine the role of the hormone 17-β...

This $500,000 National Science Foundation project grant supports research to advance the biom anufacturing of extracellular vesicles through the integration of human induced pluripotent stem cell technology, genome engineering, and membrane nanofabrication. The primary recipient is Syracuse University, with Rochester Institute of Technology serving as a sub-awardee. Under the Biological Sciences program (CFDA 47.074), the grantees will work to generate a stable human iPSC line with enhanced EV...

Federal Grant Award Summary Albany Medical College received a $164,000 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 6, 2025, with completion targeted for May 31, 2027. The project, "Development of Conformer-Specific Anti-I-A Class II Monoclonal Antibodies," focuses on identifying and characterizing novel monoclonal antibodies (MAbs) that selectively recognize...

This Project Grant award of $240,300 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to develop bispecific antibodies (bAbs) that can efficiently penetrate the blood-brain barrier and deliver neutralizing antibodies against Eastern Equine Encephalitis Virus (EEEV) to the brain. The project will evaluate the therapeutic effectiveness of the bAbs compared to alternative antibody delivery methods...

Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $761,840 to The Trustees of Columbia University in the City of New York (Health Sciences Division) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 5, 2025, with a completion date of July 31, 2030. This research project addresses cardiac allograft vasculopathy (CAV), the leading cause of morbidity and mortality following heart transplantation, by...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $7,105,240 Project Grant under the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program to the University of California, Davis. This funding will support a collaborative HIV vaccine research program, referred to as OPTI-FLIP, that aims to develop a vaccine regimen leveraging cooperative interactions between antibody and T-cell immune responses. The key research activities funded under this grant...

Federal Grant Award Summary Emmune Inc. received a $1.84 million Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 17, 2025, with completion targeted for May 31, 2026. The award supports the development of a non-viral gene therapy platform utilizing ECD4-IG, a therapeutic protein designed to suppress HIV replication through a single intramuscular injection. ECD4-IG functions as an...

Federal Project Grant Award Summary Case Western Reserve University received a $233,790 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 20, 2026, with completion targeted for January 31, 2028. The research project, conducted at the university's Cleveland, Ohio location in affiliation with University Hospitals of Cleveland, investigates cytomegalovirus (CMV) reactivation...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859), is focused on developing a novel high-throughput, high-content imaging platform for analyzing extracellular vesicles (EVs) at the single-particle level. The $298,999 award to Numentus Technologies Inc. will fund the construction, testing, and application of this platform to detect and characterize EV subpopulations, including...