Project Grant R21AG101323
Award Date 5/1/26
Completion Date 4/30/28
Dollars Obligated $501K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
San Diego, CA 92121, USA
Similar Awards
- Federal Grant Award Summary The Buck Institute for Research on Aging received a $809,486 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective February 1, 2026, through January 31, 2031. This award supports research investigating the role of Oxidation Resistance 1 (OXR1) and retromer proteins in brain aging and Alzheimer's disease and related dementias (ADRD). The research leverages both Drosophila melanogaster (fruit fly) models...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded Scripps Research Institute a $878,190 Project Grant on September 15, 2025, under the Aging Research program (CFDA 93.866) to investigate a druggable mito-nuclear feedback mechanism that preserves mitochondrial and synaptic function in old age. The research will be conducted through May 31, 2030, and focuses on understanding how mitochondrial decline contributes to Alzheimer's disease and related dementias (ADRD). Scripps...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded J. David Gladstone Institutes a Project Grant totaling $1,587,554 under the Aging Research program (CFDA 93.866) to conduct biomedical research investigating mitochondrial deoxyribonucleic acid (mtDNA) compaction and its relationship to somatic mutation accumulation across the human lifespan. The research project, initiated on June 17, 2025, and scheduled for completion by April 30, 2030, will deliver scientific...
- Federal Project Grant Award Summary The Scripps Research Institute received a $506,000 Project Grant from the National Institute on Aging (CFDA 93.866 - Aging Research) awarded on August 15, 2025, with a completion date of July 31, 2027. Under this award, the institute will conduct research on engineering synthetic biomolecular condensates (BMCs) for targeted autophagy modulation. The research will develop and validate a novel BMC-based tool using PopTag, a synthetic BMC platform, to create an...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded J. David Gladstone Institutes a Project Grant of $1,459,072 on August 1, 2025, under the Aging Research program (CFDA 93.866) to conduct research on Alzheimer's Disease (AD)-related neurological dysfunction. The research will deliver scientific knowledge and methodological innovations focused on understanding how inhibitory interneurons—specifically parvalbumin (PVALB) and somatostatin (SST) cell types—contribute...
- Federal Grant Award Summary The Broad Institute of MIT and Harvard received a $610,836 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) effective September 1, 2025, through May 31, 2030. This award supports research on the genetic dissection of mitochondrial-nuclear (mitonuclear) interactions in aging and neurodegenerative disease, with particular focus on Alzheimer's disease and related dementias (ADRD). The research leverages two key...
- This $1,031,595 project grant from the National Institute on Aging, part of the Department of Health and Human Services, supports research under the Aging Research program (CFDA 93.866). The awardee, Dana-Farber Cancer Institute, will define the landscape and mechanisms of protein redox regulation during aging. Specifically, the Institute will systematically map cysteine oxidation networks in mouse tissues to determine their role in coordinating protein complex assemblies relevant to age-related...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded UC San Diego a Project Grant totaling $498,366 (Award Date: September 1, 2025; Completion Date: August 31, 2027) under the Aging Research program (CFDA 93.866) to develop and validate a novel platform for single-cell analysis of biological aging biomarkers. The project focuses on designing and implementing arrays of bottomless microscopic conical wells with picoliter volumes to capture, immunolabel, and conduct...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded The Salk Institute for Biological Studies a Project Grant of $620,441 under the Aging Research program (CFDA 93.866), with an award date of February 15, 2026 and ultimate completion date of January 31, 2031. This research initiative focuses on characterizing activity-dependent changes to neuronal populations in the spinal dorsal horn during aging and determining the functional consequences of dorsal horn remodeling for...
- Federal Project Grant Award Summary Epicypher, Inc. received a $1.25M Project Grant award from the National Institute on Aging (CFDA 93.866: Aging Research) effective September 20, 2025, with completion targeted for May 31, 2027. In partnership with Dr. Nicolas Young at Baylor College of Medicine, Epicypher is developing AgingPTM™, a novel platform technology designed to identify and study aging-associated combinatorial histone post-translational modifications (HPTMs) in tissue samples. The...