Project Grant R16GM165339
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Virginia $782,459 on March 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the impact of obesity on microvascular insulin action and cardiorespiratory fitness in individuals with Type 1 Diabetes. The research will test the hypothesis that endothelial oxidative stress and microvascular insulin resistance lead to reduced skeletal and...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Miami $534,988 on August 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the direct effects of physical exercise on pancreatic beta-cell function and mass. The project will employ high-resolution microscopy, single-cell transcriptional and epigenetic profiling, living tissue physiological assessment, and human islet transplantation...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Arkansas for Medical Sciences $717,457 on February 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate metabolic rewiring of T cells and the pathogenic connection between diabetes and hypertension. The research examines immune-metabolic crosstalk in the progression from type 2 diabetes to hypertension using a high-fat diet-induced...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $803,565 to the University of California, Davis on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop and characterize an orally delivered nanodrug for metabolic disease treatment. The project targets metabolic dysfunction-associated steatohepatitis (MASH) and type 2 diabetes mellitus by addressing gut dysbiosis and restoring impaired signaling...
- The National Heart Lung and Blood Institute awarded New York University a project grant of $2,567,368 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate macrophage signaling, cell-intrinsic and cell-cell communications, and ischemic injury in diabetes through the RAGE/DIAPH1 axis. The research focuses on mitochondrial dysfunction in cardiac and skeletal muscle cells driven by RAGE ligands in diabetes and hypoxia/ischemia conditions. Project 1...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Oklahoma Health Sciences Center $100,228 on September 30, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to support research training on skeletal muscle MIRO1's role in insulin resistance and type 2 diabetes complications. The award funds an F31 fellowship supporting two specific research aims: determining whether MIRO1 (mitochondrial Rho-GTPase 1) is...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Arkansas Colleges of Health Education $646,459 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct research on novel mechanisms promoting energy intake compensation in response to aerobic and resistance exercise. The research addresses how individuals compensate for energy expended during exercise by increasing food intake, thereby limiting weight...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of California, Davis $782,890 on August 15, 2026, for Project Grant R01DK148505 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research examines how alpha cells in the pancreas regulate glucose through distinct and sometimes opposing mechanisms during obesity and weight loss. Alpha cells overproduce glucagon in obesity and insulin resistance,...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $451,000 Project Grant to The Regents of the University of California, San Francisco on September 5, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports a two-year research initiative (completion by August 31, 2027) investigating the role of microRNAs in adipose tissue dysfunction among people with HIV (PWH) who...
- Federal Project Grant Award Summary The University of California, San Francisco received a $2.97 million Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective September 4, 2025, with completion targeted for August 31, 2029. This award supports translational research investigating the regulatory mechanisms by which fatty acids control protein...
The National Institute of General Medical Sciences awarded the University of The Pacific $122,065 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the effects of moderate and high intensity interval exercise on vascular and metabolic function across prediabetes and diabetes. The research examines how different exercise intensities affect aortic and mesenteric arterial reactivity and metabolic outcomes in UC Davis type 2 diabetes mellitus rats of both sexes. The project tests the hypothesis that moderate and high intensity interval exercise confer vascular and metabolic benefits with effects dependent on sex and diabetes status, with greater benefits in males during prediabetes and in females during diabetes. Work is structured across two integrated aims: determining the impact of exercise on arterial reactivity across prediabetes and diabetes stages, and investigating mechanisms through which exercise enhances endothelium-dependent vasorelaxation by modulating endothelin-1 signaling and nitric oxide synthase phosphorylation. Performance occurs in Stockton, California. The period of performance runs from August 1, 2026, through March 31, 2030. The award is classified as a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $122.1k | 7/21/26 |