Project Grant R16GM159792
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will provide $350,000 to Creighton University to investigate the effects of environmental enrichment on the abuse liability of minor cannabinoids such as delta-8-THC and CBD. The research aims to determine if adolescent exposure to high- or low-novelty environments can alter sensitivity to these cannabis compounds using animal models....
- This Project Grant award of $144,950.00 from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) aims to evaluate the expression, function, and immunomodulatory potential of endocannabinoid receptors, including TRPV2 and PPAR-A, as well as cannabidiol (CBD), in microglia in the context of HIV. The research goal is to investigate how the endocannabinoid system can modulate the HIV-induced inflammatory response in microglia, which is a key driver of...
- This federal Project Grant award of $104,118.00 from the National Center for Complementary and Integrative Health (NCCIH), under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), is funding a research project to investigate the human metabolism of the minor cannabinoid cannabichromene. The award was granted on June 19, 2025 and the ultimate completion date is January 31, 2028. The research is being conducted by the University of Colorado-Denver, a prominent...
- This federal Project Grant award of $385,638 was provided by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, under the Drug Use and Addiction Research Programs (CFDA 93.279). The purpose of the grant is to conduct research on the neurobehavioral consequences of chronic exposure to synthetic cannabinoids, also known as "synthetic marijuana", across different stages of lifespan development and between sexes. The research aims to elucidate the...
- This federal Project Grant award of $390,000.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research on the structural dynamics of G protein-coupled receptor (GPCR) oligomerization and its impact on cellular localization and signaling. The 5-year award, effective August 1, 2025, will fund investigations into the complexes formed between GPCRs, G proteins, β-arrestins, and GPCR kinases,...
- The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $1,320,580 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The Washington University in Missouri. The grant will fund preclinical studies to evaluate the analgesic potential of a novel, peripherally-restricted cannabinoid type 1 receptor (CB1R) agonist called VIP36. The key objectives are to assess VIP36's efficacy in mouse models of post-traumatic headache,...
- The National Science Foundation (NSF) awarded a $750,000 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of South Dakota. The grant, awarded from July 1, 2024 to June 30, 2027, will support research to understand the dual pain-increasing and pain-decreasing effects of the endocannabinoid system in the medicinal leech Hirudo verbana. The project aims to examine the neuronal mechanisms by which different patterns of neural activity can trigger pro- versus...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), has awarded Clemson University a $312,559 project grant for the period of September 1, 2025 to August 31, 2030. The grant supports the development of new deoxygenative functionalization methods to access medicinally valuable chiral amines and fluorinated compounds from alcohols and carboxylic acids. The research aims to enable one-step, stereospecific...
- This Project Grant award of $384,896.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop novel peptide-based biomaterials that can directly modulate cell and tissue responses. The goal is to create advanced biomodulatory materials, such as self-adjuvanting vaccines, anti-inflammatory therapeutics, cell-targeted cancer therapies, and bone regenerative products, to address challenges in...
- The U.S. National Institute of General Medical Sciences (NIGMS) awarded a $416,625 Project Grant to Saint Louis University under the Biomedical Research and Research Training program (CFDA 93.859) to develop innovative optical tools to control endogenous G protein-coupled receptors (GPCRs) in unmodified cells and in vivo. The project aims to: (1) enable optical control of endogenous GPCRs, (2) control GPCRs and endogenous G proteins at specific subcellular locations like the Golgi and nuclear...
The National Institute of General Medical Sciences (NIGMS) awarded a $112,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Harris-Stowe State University in St. Louis, Missouri. The grant, which runs from September 1, 2025 to August 31, 2029, will fund research to understand the molecular-genetic mechanisms of cannabidiol (CBD) action in Drosophila, a model organism, in order to elucidate the potential use of CBD for treating neuropsychiatric and neurological disorders. The project builds on preliminary studies conducted by undergraduate researchers at Harris-Stowe State University, an HBCU, and will involve investigating the conserved neurological pathways affected by CBD across invertebrate and vertebrate species.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $112.0k | 8/31/25 |