Project Grant R16AI184350

Award Date 9/1/24
Completion Date 8/31/28
Dollars Obligated $175K
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
California, USA
Similar Awards
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $490,093 to the University of Maryland, College Park to develop a rapid antibiotic susceptibility testing platform. The goal is to create a microfluidic-enabled technology that can isolate small numbers of bacteria directly from whole blood, identify bacterial pathogens, and evaluate their antibiotic response within 75...
This Project Grant award, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to optimize the regimen structure and characterize the pharmacokinetics and pharmacodynamics of a multi-phage cocktail therapy for treating extensively drug-resistant Pseudomonas aeruginosa infections. The $714,053 award, with a period of performance from August 2024 to July 2029, will fund the development of a...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $205,000.00 to The Trustees of Princeton University to examine the influence of chromosome copy number on Pseudomonas aeruginosa persister cells that tolerate fluoroquinolone antibiotics. The key research objectives are to: 1) Measure chromosome copy number in individual P. aeruginosa cells and correlate this...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will provide $728,695 to the University of Arkansas for Medical Sciences (UAMS) from September 1, 2024 to August 31, 2029. The award will fund research to investigate mechanisms of cefiderocol resistance and heteroresistance in carbapenem-resistant gram-negative pathogens. Specific objectives include studying preexisting cefiderocol resistance and...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $212,169 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Johns Hopkins University. The grant supports research focused on advancing the PI's expertise in mentoring trainees in antimicrobial resistance (AMR) research. Specifically, the PI plans to expand their knowledge of molecular mechanisms of resistance, incorporating site-directed mutagenesis and pharmacodynamic...
This federal Project Grant award was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $1,350,312 award is supporting the development of a rapid, phenotypic drug susceptibility testing system for tuberculosis (TB). The key products and services being delivered under this grant include: Developing and optimizing novel fluorescent trehalose probes (3HC-TRE and RMR-TRE) to specifically detect...
This $569,210 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research to structurally and functionally characterize three key proteins responsible for antimicrobial peptide/colistin resistance in Gram-negative bacteria, including high-threat pathogens like carbapenem-resistant Acinetobacter baumannii and Enterobacteriaceae. The research aims to develop...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $749,417 to President and Fellows of Harvard College to conduct research focused on developing novel antibiotics to address the challenge of multi-drug resistant bacterial pathogens. The research aims to synthesize and evaluate new antibiotic compounds that target the lipoprotein transport pathway in...
The National Science Foundation awarded $905,966 under the Engineering (47.041) federal grant program to The Regents of the University of California, Berkeley from June 15, 2022 to May 31, 2027. The award will support the development and validation of a targeted long-read DNA sequencing approach to enable enrichment of antibiotic resistance genes and flanking regions from metagenomic samples. This is intended to facilitate detection of low-abundance antibiotic resistance gene targets and their...
This federal Project Grant award of $340,298 from the National Institute of Allergy and Infectious Diseases (NIAID) under CFDA 93.855 - Allergy and Infectious Diseases Research aims to develop a new, cost-effective method for sequencing the genome of Mycobacterium leprae, the bacteria that causes leprosy. The grant will fund research to evaluate the sensitivity and accuracy of a selective whole genome amplification (SWGA) technique for sequencing M. leprae DNA from both laboratory-infected and...

This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $175,000.00 to California State University, Fresno to develop a decentralized antimicrobial resistance (AMR) surveillance system in resource-limited settings. The project aims to assess the detection of drug-resistant bacteria and antimicrobial bacteriophages using cost-efficient long-read sequencing on Flongle platforms. This effort focuses on monitoring locally sourced metagenomic samples and drug-resistant Pseudomonas aeruginosa associated with contaminated eyedrops, which have led to outbreaks and fatalities. The goal is to establish a community-wide surveillance system that can efficiently track local infection outbreaks in terms of time, accuracy, and cost, encompassing a broad spectrum of sample types including medicinal and agricultural products. The award period runs from Sep 1, 2024 to Aug 31, 2028.

Generated 6/17/25, 2:50 AM