Project Grant R15NS149157
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded The Medical University of South Carolina $100,228 on December 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on complement-mediated mechanisms of injury and repair in germinal matrix hemorrhage, a leading neurological injury of prematurity....
- The National Institute of Neurological Disorders and Stroke awarded the University of Missouri System $329,234 on June 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support research on synaptic function during metabolic stress. The research project, titled "Transforming Synapses to Operate During Extreme Metabolic Dysfunction," investigates how the brain maintains synaptic performance when energy delivery...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded Drexel University $547,255 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of the functional organization of descending neuron networks that control collision-avoidance behavior. Using electron microscopy connectomes of the central nervous system at synaptic...
- The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, awarded Tulane University $625,392 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of microglial activation and inflammatory cytokine secretion as mechanisms driving central nervous system consequences of intermittent pathogen exposure. The recipient will investigate viral...
- The National Institute of Neurological Disorders and Stroke awarded the University of North Carolina at Chapel Hill $439,069 on June 22, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support basic research on the molecular and genetic mechanisms governing astrocyte morphological development. The research uses molecular-genetic tools and live-imaging techniques in Drosophila and zebrafish model systems to understand how...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $711,256 to the University of Arizona on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research defining how neurons drive outcomes in CNS toxoplasmosis caused by Toxoplasma gondii. The research addresses a mechanistic gap in understanding neuron-T....
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded $671,988 to the Winifred Masterson Burke Medical Research Institute, Inc. on September 11, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The recipient will conduct research on cross-talk between sarmoptosis and ferroptosis in hemorrhagic stroke, specifically...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $420,750 to West Virginia University Research Corporation on August 27, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Project Grant R21NS151357). The award funds research into sleep-driven reorganization of excitatory and inhibitory synaptic nanoarchitecture, investigating how...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded Yale University $667,613 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining ferroptosis—iron-induced programmed cell death—in erythrocytes within intracerebral hemorrhage hematomas. The project investigates how heme induces...
- The National Institute of Neurological Disorders and Stroke awarded $588,794 to the University of South Florida on July 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating the functions of microglial laminin in blood-brain barrier repair and microglial activation following ischemic stroke. The research encompasses three aims: examining the function of microglial laminin in stroke...
The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded Wake Forest University $533,623 on September 3, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating mechanisms that protect neurons from glutamate excitotoxicity during metabolic stress. The research uses avian neurons, which naturally resist the neurotoxic cascade triggered by energy depletion, as a model system to identify neuroprotection mechanisms. The project pursues three specific aims: maintaining glutamate transporter function during metabolic stress, enhancing GABAergic signaling to preserve neuronal viability, and establishing neuroprotection mechanisms in living systems. The investigator will employ patch-clamp electrophysiology, behavioral assays, and advanced microscopy to test the hypothesis. The research applies to multiple neurological conditions including stroke, respiratory arrest, Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. The award supports training for two PhD students and eight undergraduates at Wake Forest University in Winston-Salem, North Carolina. The period of performance extends from September 3, 2026, through August 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $533.6k | 9/3/26 |