Project Grant R15HL177624
- This federal Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $422,894 to support research examining the interactive effects of cardiorespiratory fitness and adiposity on the recovery of impaired glucose and vascular control following a period of physical inactivity. The award period is from April 20, 2025 to March 31, 2028. The key objectives of the project are to: 1) investigate how existing health status...
- This Project Grant award of $110,726.00 from the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) aims to utilize data from the Molecular Transducers of Physical Activity Consortium (MoTrPAC) to characterize the molecular aging of white adipose tissue and the potential impact of endurance exercise training, with a focus on sex-specific differences. The research project led by the Pacific Northwest National...
- This Project Grant award, totaling $136,646, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) to Duke University. The funding will support a 5-year observational study to assess sex differences in physical activity (PA) participation and maintenance among individuals enrolled in cardiac rehabilitation (CR) programs. The key objectives are to: 1) identify sex differences in PA participation during and after...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $142,776 to support the career development of Dr. Sumeet Khetarpal, a physician-scientist at Massachusetts General Hospital (MGH). The 5-year award will fund Dr. Khetarpal's research to investigate the role of heart-derived proteins (myokines) in the heart's adaptation to exercise and prevention of heart failure. Key objectives include studying the contribution of...
- This Project Grant award, funded by the National Heart, Lung, and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports a feasibility study to assess the use of arteriovenous sampling to evaluate metabolic changes in the heart and legs during exercise in patients with heart failure with reduced ejection fraction. The $242,250 grant, awarded on September 1, 2025, will enable Duke University researchers to leverage interventional cardiologists and...
- This Project Grant award of $473,096 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research at the University of Utah to understand the role of lactate oxidation in the mitochondria of cardiomyocytes and its impact on cardiac function in heart failure. The key objectives are to: 1) Quantify direct versus indirect mitochondrial lactate oxidation in healthy and failing hearts; 2) Determine if mitochondrial localized MCT1 is necessary...
- This federal Project Grant award of $163,145.00 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research to investigate sex differences in cardiac macrophages and their role in right ventricular function in pulmonary arterial hypertension (PAH). The University of Colorado-Denver, the awardee, will conduct this research with the goal of understanding how female sex hormones regulate gene expression in right ventricular macrophages and...
- This federal Project Grant award of $650,028, funded by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports a research project at the University of California, Los Angeles (UCLA) to investigate the role of phosphodiesterases in regulating cyclic AMP signaling, excitation-contraction coupling, and arrhythmias in heart failure. The key objectives are to determine the differential effects of phosphodiesterase 4D signaling on cardiac...
- This $275,196 federal Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research at the University of Chicago investigating the impact of adolescent reproductive health factors on the risk of cardiometabolic disease in young adult women. The project aims to analyze longitudinal data from the Pittsburgh Girls Study to examine associations between adolescent pubertal development, sexual health, and pregnancy history with...
- This federal Project Grant award of $308,799.00 was provided by the Department of Health and Human Services (HHS) National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The award supports a research project titled "Multi Omics Mapping of Exercise-Induced Interorgan Communication" at The Leland Stanford Junior University (Stanford University) with a period of performance from June 10, 2025 to May 31, 2026. The research project aims to...
This Project Grant award of $349,728.00 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research to identify and understand the cardiometabolic adaptations in male and female mice in response to acute and chronic exercise. The key objectives of the 3-year project are to: 1) determine the time course of the metabolic response to acute exercise in male and female mice; 2) identify the adaptations in cardiac substrate utilization and metabolic pathways in response to chronic treadmill and voluntary wheel running; and 3) evaluate the ability of exercise training to modulate cardiac metabolism in the obese heart. The project will be conducted by the awardee, Ursinus College, which has demonstrated expertise in conducting federally funded cardiovascular research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $349.7k | 8/20/25 |