Project Grant R15ES037888
- The Project Grant award of $3,133,754 from the National Institute of Environmental Health Sciences (NIEHS, CFDA 93.113 Environmental Health) aims to comprehensively assess the exposome (a person's cumulative lifetime exposures) and epigenome in a Michigan cohort to determine how they associate with amyotrophic lateral sclerosis (ALS) risk and survival. The research, conducted by the Regents of the University of Michigan, seeks to gain insight into ALS disease etiology by examining the...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), awarded a $306,842 project grant to Anchorchem LLC on Jul 19, 2025. The grant aims to address the global health threat posed by harmful algal blooms (HABs) and the associated risks from cyanopeptides, specifically anabaenopeptins (ABPs). The project seeks to create a stable supply chain of these compounds to enable critical biological studies needed to assess their...
- The University of Illinois was awarded a $108,512 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The grant, titled "LIPID-BASED INTERVENTIONS TO MITIGATE THE IMPACT OF ARSENIC ON MICROGLIAL FUNCTION AND NEUROBEHAVIOR", will fund research to investigate how the essential fatty acid docosahexaenoic acid (DHA) can protect against the neurobehavioral impacts of arsenic exposure. The...
- This $400,847 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), supports research at Louisiana State University (LSU) to investigate the role of noradrenergic signaling in mediating lead-induced alterations in stress responses. The research aims to delineate how early developmental exposure to lead disrupts noradrenergic signaling through the locus coeruleus, and how these neurological...
- The National Institute of Environmental Health Sciences (NIEHS) awarded a $441,529 Project Grant under the Environmental Health (CFDA 93.113) federal grant program to the University of Georgia Research Foundation, Inc. (UGA Research Foundation) on November 15, 2024. The grant supports research to elucidate the role of epitranscriptomic mechanisms, specifically N6-methyladenosine (m6A) RNA modification, in regulating astrocyte activation and neuroimmune dysfunction induced by chronic exposure...
- This $5,453,538 Project Grant was awarded on September 15, 2025 by the National Institute of Environmental Health Sciences (NIEHS), which administers the Environmental Health federal grant program (CFDA 93.113). The grant was awarded to New York University School of Medicine to investigate the accumulation of micro- and nanoplastic particles in mammalian tissues, including human exposure pathways, tissue deposition, and potential health impacts. Key objectives include quantifying MNP...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health (NIH), under the Environmental Health federal grant program (CFDA 93.113), supports research on the mechanisms of manganese-induced neurotoxicity via the leucine-rich repeat kinase 2 (LRRK2) protein. The $682,698 award to Florida A&M University (FAMU) aims to investigate how elevated manganese levels, as seen in occupational or environmental exposures, impact the...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $525,824 Project Grant to Neurolux Inc. in Northfield, IL. The grant aims to commercialize an Electromechanically Monitored Engineered Heart Tissue (EMEHT) platform developed at Northwestern University. Key deliverables include: 1) Developing a consumable electronics fabrication process to meet design criteria for high-throughput EMEHT studies, and 2)...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), awarded a $108,514 project grant to The Pennsylvania State University (Penn State) to characterize the pathway by which nanoplastics can be transported from the nose into the central nervous system (CNS). The key research objectives are to investigate the cells involved in this "nose-to-brain" pathway and determine how factors such as sex, age,...
- This Project Grant award of $456,328 from the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health (NIH), is funding a study titled "Patterns of Autoimmune Biomarkers Among Metal/Metalloid and Organochemical-Exposed Native American/Alaska Native Tribal Members". The study aims to quantify levels of per- and polyfluoroalkyl substances (PFAS) and toxic metals/metalloids in serum and urine samples from over 1,100 tribal members across 15...
The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $484,122 Project Grant to Black Hills State University (BHSU) on August 20, 2025. The grant supports research to elucidate the mechanisms of beta-methylamino-L-alanine (BMAA) neurotoxin-induced toxicity and to develop and test novel aptamer inhibitors of BMAA's activity in human cell lines. The research aims to provide mechanistic insights into the relationship between BMAA exposure and the development of amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS/PDC), with the long-term goal of evaluating aptamer-based therapeutics in animal models. This grant funding will enable BHSU to conduct cell functional assays, signaling pathway analysis, and global gene expression studies to better understand BMAA's cellular and molecular mechanisms, as well as to develop and evaluate aptamers as potential novel inhibitors of this neurotoxin.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $484.1k | 8/19/25 |